Evidence map›Paper›PMID 41395330›Full record

ArticleJCPP advances2025

Attention Deficit Hyperactivity Disorder and other neurodevelopmental traits are associated with impact on functioning among children in the general population.

Louise Horstmann, Charlotte A Dennison, Evie Stergiakouli, Kate Langley, Joanna Martin

Abstract read
In one paragraph

Article in JCPP advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Louise HorstmannSchool of Psychology Cardiff University Cardiff UK.ORCID https://orcid.org/0009-0008-0622-348X
Charlotte A DennisonWolfson Centre for Young People's Mental Health Cardiff University Cardiff UK.ORCID https://orcid.org/0000-0002-7493-2041
Evie StergiakouliPopulation Health Sciences Bristol Medical School University of Bristol Bristol UK.ORCID https://orcid.org/0000-0003-3586-0927
Kate LangleySchool of Psychology Cardiff University Cardiff UK.
Joanna MartinWolfson Centre for Young People's Mental Health Cardiff University Cardiff UK.ORCID https://orcid.org/0000-0002-8911-3479

Funding

Wellcome Trust
6 · The paper itself

Abstract

Background: Attention Deficit Hyperactivity Disorder (ADHD) is commonly defined as a categorical diagnosis requiring clinically severe symptoms and impact on functioning. However, ADHD and other neurodevelopmental traits are also distributed continuously in the general population, where their impact on functioning is less clear. This study aimed to examine the association between ADHD impact and (a) ADHD traits, (b) co-occurring neurodevelopmental traits (autistic traits, reading ability, IQ, and pragmatic communication), and (c) genetic risk for ADHD. We also examined sex differences in these associations. Methods: We identified 12,439 children with parent or teacher reports of ADHD at ages 8 and 11 in a UK birth cohort. We examined ADHD impact (i.e., in school, home, friendships, leisure activities, and distress) as an outcome of ADHD traits and other neurodevelopmental traits at each timepoint for each informant. Polygenic scores for ADHD were derived for each child and used to predict ADHD impact. Analyses controlled for child's age at completion of ADHD measures. We also stratified analyses by sex and tested for interactions with sex. Results: ADHD traits were associated with ADHD impact across informants, ages, and sex ( Conclusions: ADHD and other neurodevelopmental traits were associated with ADHD impact in children from the general population. This reinforces the importance of inclusive environments for neurodivergent people. Clinicians and educators should consider the presence of impact and multiple neurodevelopmental difficulties when making decisions about support for all children.

Indexed as

ADHDALSPACimpact on functioningneurodevelopmental traitspolygenic scoresex differences

Identifiers

PMID41395330
PMCPMC12698278

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.