ArticleIJTLD open2025
Decentralising drug-resistant TB treatment initiation services.
Article in IJTLD open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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16 authors.
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Abstract
backgroundDrug-resistant TB (DR-TB) care coordination in Nigeria remains largely centralised, negatively impacting pre-treatment loss-to-follow-up (PTLTFU) and time-to-treatment initiation. We piloted a multi-faceted intervention and documented how the decentralisation of DR-TB services affected treatment enrolment and time-to-treatment initiation.
methodsA quasi-experimental study was conducted in Southern Nigeria. Multi-level intervention consisting of eight components was implemented in the intervention states over a 15-month period. Data were collected using desk review proformas and analysed.
resultsAt baseline, comparable proportions of people with DR-TB initiated treatment (χ
conclusionDecentralising DR-TB services significantly reduced the diagnosis-enrolment gap and time-to-treatment initiation. Our findings provide contextual evidence for the expansion of decentralised services in Nigeria.
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