Evidence map›Paper›PMID 41395321›Full record

ArticleIJTLD open2025

An assessment of video-observed treatment as an adherence support tool for patients with drug-resistant TB.

B B Nkala, A Kay, A Vasiliu, A Mandalakas, T Nkomo, L Mdluli-Dlamini, S Ngwenya, S S Thi, S Masina, J Sibanda and 2 more

Abstract read
In one paragraph

Article in IJTLD open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

B B NkalaBaylor College of Medicine Children's Foundation Eswatini, Mbabane, Eswatini.
A KayBaylor College of Medicine Children's Foundation Eswatini, Mbabane, Eswatini.
A VasiliuDepartment of Pediatrics, Baylor College of Medicine, Global TB Program, Houston, TX, USA.
A MandalakasDepartment of Pediatrics, Baylor College of Medicine, Global TB Program, Houston, TX, USA.
T NkomoEswatini National Tuberculosis Control Program, Manzini, Eswatini.
L Mdluli-DlaminiEswatini National Tuberculosis Control Program, Manzini, Eswatini.
S NgwenyaEswatini National Tuberculosis Control Program, Manzini, Eswatini.
S S ThiEswatini National Tuberculosis Control Program, Manzini, Eswatini.
S MasinaEswatini National Tuberculosis Control Program, Manzini, Eswatini.
J SibandaEswatini National Tuberculosis Control Program, Manzini, Eswatini.
S TselaEswatini National Tuberculosis Control Program, Manzini, Eswatini.
D VambeBaylor College of Medicine Children's Foundation Eswatini, Mbabane, Eswatini.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn 2017, WHO endorsed digital adherence technologies, including video-observed treatment (VOT), to support TB treatment adherence. In 2021, Eswatini implemented VOT to support adherence for drug-resistant TB (DR-TB) patients nationwide, although limited evidence exists regarding its feasibility and acceptability in low-resource settings.

methodsWe conducted 33 in-depth interviews with DR-TB patients and health care providers (HCPs), across all four regions of Eswatini to explore their experiences with VOT.

resultsThe findings indicated broad acceptance of VOT among both HCPs and patients. HCPs reported that VOT strengthened their connection with patients, facilitated adherence, and increased their confidence in treatment outcomes. While most patients found VOT user-friendly and appreciated the independence and privacy it offered, elderly patients faced challenges using smartphones, which sometimes resulted in poor-quality video submissions.

conclusionVOT is feasible and acceptable among HCPs and patients in Eswatini. Further research is needed to evaluate the impact of VOT on treatment outcomes in high-burden and low-resource settings to inform the scale-up of similar digital health interventions in comparable contexts. Strengthening digital infrastructure and providing tailored support for elderly patients could further enhance VOT effectiveness and equity.

Indexed as

digital adherence technologymobile health technologypatient-centred caretuberculosis

Identifiers

PMID41395321
PMCPMC12699967

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.