ArticleFrontiers in pediatrics2025
Diagnosing acute appendicitis in children with neutrophil-lymphocyte ratio: a cross-sectional study.
Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Diagnostic Accuracy of Inflammatory Biomarkers in Differentiating Acute Appendicitis From Other Acute Abdomen and Predicting Disease Severity: A Prospective Comparative Cross-Sectional Study.Health science reports · 2026Article
- Comparison of physical examination, laboratory and radiologic findings in the diagnosis of acute appendicitis.Northern clinics of Istanbul · 2026Article
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5 authors.
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Abstract
Background: Diagnosing acute appendicitis (AA) in children can be challenging due to atypical symptoms and the difficulty in obtaining a comprehensive history. This study aimed to evaluate the value of the neutrophil-to-lymphocyte ratio (NLR) in diagnosing AA in the pediatric population. Methods: This retrospective cross-sectional study involved 200 pediatric patients aged between 0 and 14 years of both sexes, who underwent appendectomy for suspected acute appendicitis. Data of patients were retrieved from the hospital's patient administration system database. We categorized patients into three surgical groups: Group 1, appendectomy + normal appendix ( Results: White blood cell (WBC) count, neutrophil count, and NLR were significantly higher in the acute appendicitis and complicated appendicitis groups than those in the normal appendix group and in the complicated appendicitis group than those in the acute appendicitis group. In multivariate regression, WBC count and NLR were associated with AA ( Conclusions: NLR is a potentially useful adjunctive and cost-effective diagnostic marker for AA and complicated appendicitis in the pediatric population.
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