ArticleAmerican journal of cancer research2025
Identification of colorectal cancer using enteroviral and bacterial subtypes.
Article in American journal of cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Virulome over taxonomy: refining the driver-passenger model in colorectal carcinogenesis.Frontiers in cellular and infection microbiology · 2026Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colorectal cancer (CRC) is influenced by both enteroviruses and bacteria, yet current microbial typing schemes rely primarily on bacterial data. To construct a more comprehensive microbial typing scheme for CRC, this study integrated enteroviral and bacterial profiling data from fecal samples of 414 healthy controls (NCs), 151 advanced adenoma (AAs) patients, and 255 CRC patients using Illumina sequencing. Metabolites and trace elements were analyzed via liquid chromatography and ICP-MS, respectively. Microbial subtyping was performed with ConsensusClusterPlus based on combined viral and bacterial sequencing data, leading to the identification of two initial viral subtypes (V1, n=309; V2, n=511). The V2 group was further split into two bacterial subtypes (V2B1, V2B2), yielding three distinct microbial subtypes. Disease ratios (CRCs&AAs/NCs) were 1.06 (V1), 0.67 (V2B1), and 1.29 (V2B2). V1 showed increased
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