Evidence map›Paper›PMID 41394975›Full record

ArticleFrontiers in bioengineering and biotechnology2025

Establishment and validation of a three-dimensional finite element model for degenerative lumbar scoliosis.

Wei Guo, Wanzhong Yang, Jie Yang, Xin Zhao, Honglai Zhang, Zemin Wang, Shiyong Wang, Rong Ma, Zhaohui Ge

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Pathogenic mechanisms of adult degenerative scoliosis.Frontiers in cell and developmental biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wei Guo *Department of Orthopedics, General Hospital of Ningxia Medical University, Yinchuan, China.
Wanzhong Yang *Department of Orthopedics, General Hospital of Ningxia Medical University, Yinchuan, China.
Jie Yang *Department of Orthopedics, General Hospital of Ningxia Medical University, Yinchuan, China.
Xin ZhaoDepartment of Orthopedics, General Hospital of Ningxia Medical University, Yinchuan, China.
Honglai ZhangThe First Clinical Medical College, Ningxia Medical University, Yinchuan, China.
Zemin WangThe First Clinical Medical College, Ningxia Medical University, Yinchuan, China.
Shiyong WangThe First Clinical Medical College, Ningxia Medical University, Yinchuan, China.
Rong MaDepartment of Orthopedics, General Hospital of Ningxia Medical University, Yinchuan, China.
Zhaohui GeDepartment of Orthopedics, General Hospital of Ningxia Medical University, Yinchuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The objective of this study was to construct a three-dimensional finite element model of degenerative lumbar scoliosis (DLS) and validate its effectiveness, providing a reliable theoretical tool for optimizing surgical plans and biomechanical research. Methods: A 3D finite element model (FEM) of Lenke-Silva type IV DLS was constructed from patient CT data using Mimics, Geomagic Warp, SolidWorks, and ANSYS, incorporating cortical bone, cancellous bone, and intervertebral discs with defined material properties and contact relationships. Geometric validation was performed by comparing vertebral alignment and offset with radiographic measurements, while biomechanical validation involved applying a 400N axial load and 7.5 Nm torque (flexion/extension, lateral bending, and axial rotation) to L1 and comparing the results with established literature data. Results: The successfully constructed L1-S1 DLS finite element model comprised 1,255,696 tetrahedral elements (1.5 mm mesh size) and 1,919,710 nodes. Geometric validation demonstrated excellent agreement with radiographic measurements, showing <1 error in Cobb and lumbar lordosis, and <1.76 mm deviation in vertebral centroid alignment. Biomechanical validation revealed that the segmental range of motion (ROM) at L2-3 through L4-5 under 7.5 Nm loading conditions (flexion/extension, lateral bending, and axial rotation) matched established literature data, confirming model reliability. Conclusion: The DLS three-dimensional finite element model constructed in this study exhibits high anatomical fidelity and biomechanical reliability, enabling dynamic simulation of spinal mechanical behavior under complex loads, thereby providing an experimental foundation for surgical plan optimization and complication prediction.

Indexed as

biomechanical effectsdegenerative lumbar scoliosisfinite element modelgrid sensitivity analysismodel validation

Identifiers

PMID41394975
PMCPMC12695814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.