Evidence map›Paper›PMID 41394973›Full record

ArticleFrontiers in bioengineering and biotechnology2025

BEES-HAUS preventing urethral stricture recurrence by restoring the integrity of urothelium and its further simplified version, the BHES-HAUS.

Akio Horiguchi, Surya Prakash Vaddi, Senthilkumar Rajappa, Senthilkumar Preethy, Samuel J K Abraham

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A hybrid combination ofFrontiers in urology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Akio HoriguchiDivision of Reconstruction, Center for Trauma, Burn and Tactical Medicine, National Defense Medical College Hospital, Tokorozawa/Saitama, Japan.
Surya Prakash VaddiDepartment of Urology, Surya Kidney Centre, Hyderabad, India.
Senthilkumar RajappaAntony- Xavier Interdisciplinary Scholastics (AXIS), GN Corporation Co. Ltd., Kofu, Japan.
Senthilkumar PreethyThe Fujio-Eiji Academic Terrain (FEAT), Nichi-In Centre for Regenerative Medicine (NCRM), Chennai, Tamil Nadu, India.
Samuel J K AbrahamAntony- Xavier Interdisciplinary Scholastics (AXIS), GN Corporation Co. Ltd., Kofu, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagram illustrating interventional treatment approaches for urethral stricture, emphasizing urothelial integrity in preventing stricture recurrence. It compares procedures such as balloon dilatation and urethrotomy which leave the sub-urothelium exposed to urine leading to inflammation to that of procedures such as BEES-HAUS in which transplanted buccal mucosal cells and in BHES-HAUS transplanted buccal tissue bits, both mixed with Festigel, engraft and restore the urothelial integrity. BEES-HAUS involves a two-week in vitro culture, while BHES-HAUS processes tissue in the operating room in single sitting. Both methods aim for effective urethral treatment using autologous buccal mucosal epithelium.Diagram illustrating interventional treatment approaches for urethral stricture, emphasizing urothelial integrity in preventing stricture recurrence. It compares procedures such as balloon dilatation and urethrotomy which leave the sub-urothelium exposed to urine leading to inflammation to that of procedures such as BEES-HAUS in which transplanted buccal mucosal cells and in BHES-HAUS transplanted buccal tissue bits, both mixed with Festigel, engraft and restore the urothelial integrity. BEES-HAUS involves a two-week in vitro culture, while BHES-HAUS processes tissue in the operating room in single sitting. Both methods aim for effective urethral treatment using autologous buccal mucosal epithelium.

Indexed as

BEES-HAUSBHES-HAUSbuccal mucosaurethral strictureurothelium

Identifiers

PMID41394973
PMCPMC12695836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.