Evidence map›Paper›PMID 41394967›Full record

ArticleFrontiers in bioengineering and biotechnology2025

Iso-height axis correlates with collateral ligament balance in medial compartment knee osteoarthritis.

Zheng Jiang, Xiaolong Lü, Nan Zheng, Zhaoyi Fang, Yanjie Mao, Axiang He, Xuancheng Zhang, Weiming Lin, Bingbo Bao, Xianyou Zheng and 1 more

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Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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11 authors.

Zheng JiangDepartment of Orthopedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiaolong LüSchool of Biomedical Engineering & Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Nan ZhengSchool of Biomedical Engineering & Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Zhaoyi FangBiodynamics Lab, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, United States.
Yanjie MaoDepartment of Orthopedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Axiang HeDepartment of Orthopedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xuancheng ZhangDepartment of Orthopedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Weiming LinDepartment of Orthopedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Bingbo BaoDepartment of Orthopedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xianyou ZhengDepartment of Orthopedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wanjun LiuDepartment of Orthopedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: A dynamic iso-height Axis (IHA) was invented based on knee flexion motion and supposed to be a target to restore knee soft tissue balance, which is critical in knee surgeries. This study aims to validate the correlation between IHA and the elongation patterns of the medial and lateral collateral ligaments (MCL and LCL). Methods: Twenty-six patients with unilateral MCKOA and intact contralateral knees were enrolled. Three-dimensional models of knee were built from CT scan. The TEA, GCA and footprints of superficial, deep MCL (sMCL, dMCL) and LCL were determined based on knee surface models. Each ligament was divided into three bundle according to the anatomical feature. Patients performed stair climbing under the surveillance of dual fluoroscopic imaging system (DFIS), and the elongation of collateral ligament bundle and IHA positions of bilateral knees were calculated. Results: Compared to the native side, the sMCL and dMCL bundles were shorter (mean -2.9% and -6.2%, respectively), while the LCL medial and posterior bundles were significantly longer (mean 4.5%) in MCKOA knees. There were no significant differences in the IHA between the medial compartment knee osteoarthritis (MCKOA) knee and the native knee during daily extension. Besides, the iso-height point on the lateral femoral condyle geometrical centre axis (GCA) plane nearly overlapped with the lateral GCA point. There was a significant correlation between the differences of two-sided IHA positions and the differences of two-sided collateral ligament elongations (P < 0.01). Conclusion: This study firstly validated the correlation between IHA and the elongation patterns of the MCL and LCL, suggesting that IHA can reflect longitudinal soft tissue balance state of the knee joint. This finding provides new insights for improving design and planning in future clinical interventions.

Indexed as

collateral ligamentflexion axesIHAMCKOAsoft tissue balance

Identifiers

PMID41394967
PMCPMC12695765

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