Evidence map›Paper›PMID 41394966›Full record

ReviewFrontiers in bioengineering and biotechnology2025

Expanding the CRISPR/Cas toolkit: applications in proteomics and theranostics.

Ashwini Punde, Saurabh Dey, Riya Pandire, Arindam Bhattacharjee, Chinmoy Patra

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ashwini PundeDepartment of Developmental Biology, Agharkar Research Institute, Pune, India.
Saurabh DeyDepartment of Developmental Biology, Agharkar Research Institute, Pune, India.
Riya PandireDepartment of Developmental Biology, Agharkar Research Institute, Pune, India.
Arindam BhattacharjeeDepartment of Developmental Biology, Agharkar Research Institute, Pune, India.
Chinmoy PatraDepartment of Developmental Biology, Agharkar Research Institute, Pune, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional methods available for genome editing have proven non-specific, labour-intensive, and time-consuming. In this context, CRISPR/Cas technology represents a significant breakthrough. It is derived from a sophisticated microbial defence system consisting of clustered regularly interspaced short palindromic repeats, or CRISPR, and the RNA-guided DNA endonuclease Cas. Beyond its original role in genome editing, CRISPR continues to play a major role in the field of proteomics, functional genomics, and molecular therapy. Animal models, including mice,

Indexed as

CRISPR-Cas systemgenome-engineeringprotein-chromatin interactionprotein-protein interactionproteomicstheranostics

Identifiers

PMID41394966
PMCPMC12695753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.