Evidence map›Paper›PMID 41394936›Full record

ArticleClinical case reports2025

Remimazolam-Induced Paradoxical Reaction in a Bipolar Patient: A Case Report.

Zhifu Zhao, Li Liu, Xianjie Zhang

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhifu ZhaoDepartment of Anesthesia Deyang People's Hospital Deyang China.ORCID https://orcid.org/0009-0000-7713-7900
Li LiuDepartment of Anesthesia Deyang People's Hospital Deyang China.
Xianjie ZhangDepartment of Anesthesia Deyang People's Hospital Deyang China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This first reported case of remimazolam-induced paradoxical reaction (PR) in a bipolar disorder patient highlights that GABAergic dysfunction may heighten PR risk. Flumazenil effectively reversed the symptoms, underscoring the need for caution and preparedness when using benzodiazepines in this vulnerable population.

Indexed as

bipolar disorder (BD)gamma‐aminobutyric acid (GABA)paradoxical reaction (PR)remimazolam

Identifiers

PMID41394936
PMCPMC12695475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.