Evidence map›Paper›PMID 41394907›Full record

ArticleFrontiers in veterinary science2025

Efficacy of nutraceutical supplements containing

Roberto Ciarcia, Consiglia Longobardi, Valeria Iervolino, Tommaso Manenti, Francesco Ferrucci, Iolanda Veneruso, Valeria D'Argenio, Antonio Rubino, Alessandra Pelagalli, Pietro Lombardi and 1 more

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Roberto CiarciaDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Consiglia LongobardiDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Valeria IervolinoDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Tommaso ManentiBiokyma Laboratories S.r.l., Arezzo, Italy.
Francesco FerrucciDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Iolanda VenerusoCEINGE-Biotecnologie Avanzate Franco Salvatore, Naples, Italy.
Valeria D'ArgenioCEINGE-Biotecnologie Avanzate Franco Salvatore, Naples, Italy.
Antonio RubinoDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Alessandra PelagalliDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Pietro LombardiDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Sara DamianoDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Aging in dogs is a complex phenomenon characterized by metabolic, immunological and neurological alterations that may result in chronic inflammation, oxidative stress, and intestinal microbiota changing that can compromise dogs' overall health. Phytotherapeutics represents a promising approach to improve the quality of life in elderly dogs. In this study we have tested a mix of phytoextracts on seven old breed dogs to evaluate their synergistic beneficial effects. Methods: The mix was constituted by Results: Results revealed a significant reduction of C-reactive protein (CRP) for T1 and T2 respect to the basal condition (T0) ( Discussion: This study supports the hypothesis that the integration of these herbal medicines into dietary or therapeutic regimens could represent a natural and synergistic strategy to improve the quality of life, promoting the general well-being of old dogs.

Indexed as

gut microbiotainflammationmedicinal plantsoxidative stresssenior dogs

Identifiers

PMID41394907
PMCPMC12696704

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.