Evidence map›Paper›PMID 41394874›Full record

ArticleFrontiers in immunology2025

Case Report: A novel

Qi Peng, Ming Deng, Xiaomei Zeng, Qingqiu Cheng, Mingyu Xie, Siping Li, Xiaomei Lu

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qi Peng *Laboratory Department, Dongguan Children's Hospital, Dongguan, Guangdong, China.
Ming Deng *Department of Clinical Laboratory, Qingxi Hospital, Dongguan, Guangdong, China.
Xiaomei ZengLaboratory Department, Dongguan Children's Hospital, Dongguan, Guangdong, China.
Qingqiu ChengLaboratory Department, Dongguan Children's Hospital, Dongguan, Guangdong, China.
Mingyu XieRare Disease Clinic, Dongguan Children's Hospital, Dongguan, Guangdong, China.
Siping LiLaboratory Department, Dongguan Children's Hospital, Dongguan, Guangdong, China.
Xiaomei LuLaboratory Department, Dongguan Children's Hospital, Dongguan, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: PU.1 deficiency, also known as Autosomal Dominant Agammaglobulinemia-10 (AGM10), is a rare primary immunodeficiency caused by mutations in the Case description: We describe a Chinese patient with recurrent respiratory infections, agammaglobulinemia, and profound B cell lymphopenia. Initial genetic screening using a targeted Primary Immunodeficiency Panel did not identify any related pathogenic variants. Subsequent whole-exome sequencing revealed a novel Conclusion: We report the first Chinese case of PU.1 deficiency caused by a novel

Indexed as

AgammaglobulinemiaCodon, NonsenseMutationTrans-ActivatorsB-LymphocytesChinaEast Asian PeopleExome SequencingHematopoietic Stem Cell TransplantationHumansProto-Oncogene ProteinsProto-Oncogene Protein Spi-1Codon, NonsenseProto-Oncogene ProteinsProto-Oncogene Protein Spi-1Trans-Activatorsagammaglobulinemiahematopoietic stem cell transplantationPU.1 deficiencySPI1 mutationviral meningoencephalitis

Identifiers

PMID41394874
PMCPMC12698653

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.