Evidence map›Paper›PMID 41394848›Full record

ArticleFrontiers in immunology2025

Carbonic anhydrase 8 regulates basophil activation and interleukin 4 production.

Jianya Peng, Chandler B Sy, Siyuan Zhao, Arman Sawhney, Vanessa Espinosa, Marissa N Schroeter, John J Ponessa, Krupa Chavan, Alexander D Lemenze, Amariliz Rivera and 2 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jianya PengCenter for Immunity and Inflammation, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Chandler B SyCenter for Immunity and Inflammation, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Siyuan ZhaoDepartment of Pharmacology, Physiology, and Neuroscience, Rutgers. The State University of New Jersey, Newark, NJ, United States.
Arman SawhneyCenter for Immunity and Inflammation, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Vanessa EspinosaCenter for Immunity and Inflammation, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Marissa N SchroeterCenter for Immunity and Inflammation, Rutgers, The State University of New Jersey, Newark, NJ, United States.
John J PonessaCenter for Immunity and Inflammation, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Krupa ChavanCenter for Immunity and Inflammation, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Alexander D LemenzeDepartment of Pathology, Immunology and Laboratory Medicine, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Amariliz RiveraCenter for Immunity and Inflammation, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Tibor RohacsDepartment of Pharmacology, Physiology, and Neuroscience, Rutgers. The State University of New Jersey, Newark, NJ, United States.
Mark C SiracusaCenter for Immunity and Inflammation, Rutgers, The State University of New Jersey, Newark, NJ, United States.

Funding

The role of pathogen-experienced macrophage subsets in mediating lung immunity and heterologous protectionR01AI169770 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI William Clark Gause, Amariliz Rivera · 2023 to 2026
$3.1M
NIAID NIH HHS R01 AI169770
6 · The paper itself

Abstract

Carbonic anhydrase (Car) enzymes are a family of metalloenzymes that are traditionally known for their ability to regulate pH and CO

Indexed as

BasophilsCarbonic AnhydrasesInterleukin-4AnimalsCalcium SignalingDermatitis, AtopicHumansMiceMice, Inbred C57BLMice, KnockoutCarbonic AnhydrasesInterleukin-4atopic dermatitisbasophilscalcium homeostasiscarbonic anhydrase 8interleukin 4

Identifiers

PMID41394848
PMCPMC12695864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.