ReviewFrontiers in immunology2025
Human herpesvirus 6B infection in an adult with hemophagocytic lymphohistiocytosis carrying an UNC13D mutation: a case report and literature review.
Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory syndrome. The cause of onset broadly distinguishes primary from acquired HLH. However, an increasing number of carrying HLH gene mutation cases have been reported in adults, and the relationship between genetic alterations and the onset of HLH in adults is still being explored. In this case, a 43-year-old woman with a one-month history of abnormal liver function and fever presented for evaluation. Laboratory data indicated pancytopenia, elevated ferritin levels, decreased fibrinogen levels, and the presence of phagocytes in the bone marrow. She was diagnosed with HLH and found to have a heterozygous mutation in the
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