Evidence map›Paper›PMID 41394786›Full record

ArticleTrauma surgery & acute care open2025

Potential role of left atrial appendage closure in trauma patients with atrial fibrillation on anticoagulation.

Danielle Zaynab Azani, Hetal Bhakta, Albert Kazi, John Woods, Bryan Love, Mallory Jebbia

Abstract read
In one paragraph

Article in Trauma surgery & acute care open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Danielle Zaynab AzaniSurgery, Desert Regional Medical Center, Palm Springs, California, USA.ORCID https://orcid.org/0000-0002-7010-9832
Hetal BhaktaCardiology, Desert Regional Medical Center, Palm Springs, California, USA.
Albert KaziSurgery, Desert Regional Medical Center, Palm Springs, California, USA.
John WoodsSurgery, Desert Regional Medical Center, Palm Springs, California, USA.
Bryan LoveSurgery, Desert Regional Medical Center, Palm Springs, California, USA.
Mallory JebbiaDesert Regional Medical Center, Palm Springs, California, USA.ORCID https://orcid.org/0000-0002-2247-5221

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Patients with atrial fibrillation (AF) on anticoagulation (AC) have increased mortality after trauma. Left atrial appendage closure (LAAC) procedures may reduce the need for AC in patients with AF. The purpose of this study is to evaluate the outcomes of trauma patients with AF on AC compared with patients not taking AC, and assess the frequency in which trauma patients are candidates for LAAC procedures. Methods: A retrospective review of adult trauma patients after a fall was performed. AF patients on AC (+AC) were compared with patients not on AC (-AC). A CHA2DS2-VASc score is a stroke-risk stratification tool incorporating congestive heart failure, hypertension, age >75 (2 points), prior stroke (2 points), vascular disease, age 65-74, and female sex. This score was calculated for +AC patients to analyze their candidacy for LAAC. Results: +AC patients (3452 total) were found to have increased red cell (7.3% vs 6.1%, p=0.02) and plasma (2.1% vs 1.2%, p<0.001) requirements. +AC patients had increased mortality (4.6% vs 3.5%, p=0.02). 54.8% of +AC patients had a CHA2DS2VASc score of >3 and met criteria for LAAC. Conclusion: A substantial proportion of AF patients on AC meet existing criteria for LAAC. Further exploration of referral pathways may be warranted to analyze whether offering information on such procedures could reduce the risk of AC-related complications in high-risk trauma populations. Evidence level: III.

Indexed as

anticoagulationatrial fibrillation

Identifiers

PMID41394786
PMCPMC12699591

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.