Evidence map›Paper›PMID 41394672›Full record

ArticlebioRxiv : the preprint server for biology2025

Social Processing in the Amygdala: Single-Nucleus RNA-Sequencing Reveals Distinct Neuronal Responses to Dominant and Subordinate Cues.

Madeleine F Dwortz, Hans A Hofmann, James P Curley

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Madeleine F DwortzInterdisciplinary Neuroscience Program, The University of Texas at Austin, Austin, Texas, United States of America.ORCID 0000-0002-8006-6354
Hans A HofmannInterdisciplinary Neuroscience Program, The University of Texas at Austin, Austin, Texas, United States of America.ORCID 0000-0002-3335-330X
James P CurleyInterdisciplinary Neuroscience Program, The University of Texas at Austin, Austin, Texas, United States of America.ORCID 0000-0001-5546-007X

Funding

Neural processing of status signals in social hierarchiesR21MH132981 · NIMH · UNIVERSITY OF TEXAS AT AUSTIN · PI CURLEY, JAMES PATRICK, TRAINOR, BRIAN C · 2023 to 2024
$451k
NIMH NIH HHS R21 MH132981
6 · The paper itself

Abstract

The amygdala serves as a critical neural hub for interpreting social cues, with its distinct subregions and diverse neuronal populations playing specialized roles in processing these signals. This study employs single-nucleus RNA sequencing (snRNA-seq) to characterize the amygdala's neuronal responses to olfactory cues associated with social dominance, uncovering distinct activation patterns within glutamatergic and GABAergic populations. We find that a glutamatergic cluster, characterized by expression patterns closely aligned with glutamatergic

Indexed as

amygdalaGABAergic neuronsglutamatergic neuronssingle-nucleus RNA sequencingsocial dominance

Identifiers

PMID41394672
PMCPMC12697553

What OpenQuestion holds

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LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.