Evidence map›Paper›PMID 41394645›Full record

ArticlebioRxiv : the preprint server for biology2025

PULSAR: a Foundation Model for Multi-scale and Multi-cellular Biology.

Kuan Pang, Yanay Rosen, Kasia Kedzierska, Ziyuan He, Abhejit Rajagopal, Claire E Gustafson, Grace Huynh, Jure Leskovec

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kuan PangDepartment of Computer Science, Stanford University, Stanford, CA, USA.ORCID 0000-0003-3338-1738
Yanay RosenDepartment of Computer Science, Stanford University, Stanford, CA, USA.ORCID 0000-0003-1129-9645
Kasia KedzierskaAllen Institute, Seattle, WA, USA.
Ziyuan HeAllen Institute for Immunology, Seattle, WA, USA.ORCID 0000-0003-3556-8248
Abhejit RajagopalAllen Institute, Seattle, WA, USA.
Claire E GustafsonAllen Institute for Immunology, Seattle, WA, USA.ORCID 0000-0002-1437-6709
Grace HuynhAllen Institute, Seattle, WA, USA.
Jure LeskovecDepartment of Computer Science, Stanford University, Stanford, CA, USA.ORCID 0000-0002-5411-923X

Funding

Multimodality spatial analysis in prostate cancer to improve prognostic estimation and cast light into the black box of pathology artificial intelligence algorithmsR01CA296792 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Matthew R Cooperberg · 2025 to 2026
$1.4M
NCI NIH HHS R01 CA296792
6 · The paper itself

Abstract

Biology emerges from interactions across physical scales, where molecular interactions drive cellular states, which in turn orchestrate multicellular tissue functions that collectively define health and disease. However, current computational models are often constrained to single scales in isolation, failing to integrate the biology that emerges from lower to higher levels [1]. Here we present PULSAR (

Identifiers

PMID41394645
PMCPMC12697734

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.