Evidence map›Paper›PMID 41394638›Full record

ArticlebioRxiv : the preprint server for biology2025

The molecular mechanism of uptake and cell-to-cell transmission of arginine-containing dipeptide repeat proteins.

Alexandra B Sutter, Benito F Buksh, Jelena Mojsilovic-Petrovic, Casey Dalton, Nicholas A Till, Danielle C Morgan, David W C MacMillan, Robert G Kalb

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexandra B SutterDepartment of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.ORCID 0000-0003-1410-8605
Benito F BukshMerck Center for Catalysis, Princeton University, Princeton, NJ 08544.
Jelena Mojsilovic-PetrovicDepartment of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.ORCID 0000-0003-4187-7207
Casey DaltonDepartment of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.ORCID 0000-0003-0645-4460
Nicholas A TillMerck Center for Catalysis, Princeton University, Princeton, NJ 08544.
Danielle C MorganMerck Center for Catalysis, Princeton University, Princeton, NJ 08544.
David W C MacMillanMerck Center for Catalysis, Princeton University, Princeton, NJ 08544.ORCID 0000-0003-3352-4532
Robert G KalbDepartment of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.ORCID 0000-0002-2368-9280

Funding

Photoredox Catalysis Applications in Organometallics and Chemical BiologyR35GM134897 · NIGMS · PRINCETON UNIVERSITY · PI David W MacMillan · 2020 to 2026
$6.3M
Defining mechanisms underlying C9orf72-associated frontotemporal dementia with C. elegans and mammalian modelsR01NS124802 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Robert G Kalb, SAMUEL T LAMITINA · 2022 to 2026
$3.6M
RAD23 Control of ALS phenotypesR01NS122908 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KALB, ROBERT G · 2021 to 2025
$2.0M
NIGMS NIH HHS R35 GM134897NINDS NIH HHS R01 NS122908NINDS NIH HHS R01 NS124802
6 · The paper itself

Abstract

Micro-satellite repeat expansion of the 5' GGGGCC 3' sequence in the

Identifiers

PMID41394638
PMCPMC12697666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.