Evidence map›Paper›PMID 41394606›Full record

ArticlebioRxiv : the preprint server for biology2025

A geothermal amoeba sets a new upper temperature limit for eukaryotes.

H Beryl Rappaport, Natalie A Petek-Seoane, Tomáš Tyml, Felix Mikus, Kurt LaButti, Godwin Ani, Jessica K Niblo, Ethan MacVicar, Rachel M Shepherd, Ignacio de la Higuera and 11 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

H Beryl RappaportDepartment of Biology, Syracuse University; Syracuse, NY, USA.ORCID 0000-0003-3106-4579
Natalie A Petek-SeoaneDepartment of Cellular and Molecular Pharmacology, Howard Hughes Medical Institute; University of California; San Francisco, San Francisco, CA, US.ORCID 0009-0003-8253-729X
Tomáš TymlDOE Joint Genome Institute; Berkeley, California, USA.ORCID 0000-0003-2558-9846
Felix MikusDepartment of Biochemistry, University of Geneva; Geneva, Switzerland.ORCID 0000-0002-5065-4710
Kurt LaButtiDOE Joint Genome Institute; Berkeley, California, USA.ORCID 0000-0002-5838-1972
Godwin AniDepartment of Biological Sciences, Smith College; Northampton, Massachusetts, USA.ORCID 0009-0008-8684-9844
Jessica K NibloDepartment of Chemistry, Syracuse University; Syracuse, NY, USA.ORCID 0000-0001-9378-6097
Ethan MacVicarDepartment of Biology, Gonzaga University, Spokane, Washington, USA.ORCID 0009-0002-7155-8223
Rachel M ShepherdDepartment of Biology, Syracuse University; Syracuse, NY, USA.ORCID 0000-0002-0795-4996
Ignacio de la HigueraCenter for Life in Extreme Environments, Department of Biology, Portland State University; Portland, OR, USA.ORCID 0000-0002-5457-9789
Samuel J LordDepartment of Cellular and Molecular Pharmacology, Howard Hughes Medical Institute; University of California; San Francisco, San Francisco, CA, US.ORCID 0000-0002-2785-989X
Gautam DeyCell Biology and Biophysics Unit, European Molecular Biology Laboratory; Heidelberg, Germany.ORCID 0000-0003-1416-6223
Gordon V WolfeDepartment of Biological Sciences, California State University; Chico, CA, United States.ORCID 0000-0003-2220-7590
Omaya DudinDepartment of Biochemistry, University of Geneva; Geneva, Switzerland.ORCID 0000-0002-6673-3149
Shahar SukenikDepartment of Biology, Syracuse University; Syracuse, NY, USA.ORCID 0000-0003-3855-9574
Laura A KatzDepartment of Biological Sciences, Smith College; Northampton, Massachusetts, USA.ORCID 0000-0002-9138-4702
Kenneth M StedmanCenter for Life in Extreme Environments, Department of Biology, Portland State University; Portland, OR, USA.ORCID 0000-0001-6086-0238
Kristen SkruberDepartment of Cellular and Molecular Pharmacology, Howard Hughes Medical Institute; University of California; San Francisco, San Francisco, CA, US.ORCID 0000-0003-2054-6652
Frederik SchulzDOE Joint Genome Institute; Berkeley, California, USA.ORCID 0000-0002-4932-4677
R Dyche MullinsDepartment of Cellular and Molecular Pharmacology, Howard Hughes Medical Institute; University of California; San Francisco, San Francisco, CA, US.ORCID 0000-0002-0871-5479
Angela M OliverioDepartment of Biology, Syracuse University; Syracuse, NY, USA.ORCID 0000-0002-0261-0393

Funding

Assembly and function of cytoskeletal systems in eukaryotic and prokaryoticcellsR35GM118119 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MULLINS, R DYCHE · 2016 to 2025
$4.8M
Determining the molecular basis for extreme virus stability, a structure-guided approachR16GM154184 · NIGMS · PORTLAND STATE UNIVERSITY · PI Kenneth Mark Stedman · 2024 to 2026
$448k
NIGMS NIH HHS R16 GM154184NIGMS NIH HHS R35 GM118119
6 · The paper itself

Abstract

The study of temperature limits has transformed our knowledge of the boundaries of life but has been largely focused on bacteria and archaea. We isolated a novel geothermal amoeba,

Identifiers

PMID41394606
PMCPMC12697723

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.