Evidence map›Paper›PMID 41394550›Full record

ArticlebioRxiv : the preprint server for biology2025

Oncogenic

Vennesa Valentine, Abigail J Groth, Joshua Tolliver, Avneesh Saravanapavan, Spencer M Maingi, Loren B Weidenhammer, Nerissa T Williams, Lixia Luo, Matthew S Waitkus, Sheeba Jacob and 1 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Vennesa ValentineDepartment of Pharmacology & Cancer Biology, Duke University School of Medicine, Durham, NC 27710, USA.
Abigail J GrothDepartment of Radiation Oncology, Durham, NC 27710, USA.
Joshua TolliverDepartment of Radiation Oncology, Durham, NC 27710, USA.
Avneesh SaravanapavanDepartment of Biology and Global Health, Trent Hall, Durham, NC 27710, USA.
Spencer M MaingiDepartment of Radiation Oncology, Durham, NC 27710, USA.
Loren B WeidenhammerDepartment of Pathology, Davison Building, Durham, NC 27710, USA.
Nerissa T WilliamsDepartment of Radiation Oncology, Durham, NC 27710, USA.
Lixia LuoDepartment of Radiation Oncology, Durham, NC 27710, USA.
Matthew S WaitkusDepartment of Neurosurgery, Durham, NC 27710, USA.
Sheeba JacobDepartment of Radiation Oncology, Durham, NC 27710, USA.
Zachary J ReitmanDepartment of Pharmacology & Cancer Biology, Duke University School of Medicine, Durham, NC 27710, USA.

Funding

Enhancing the efficacy of Radiation Therapy for brainstem glioma by targeting ATMK08CA256045 · NCI · DUKE UNIVERSITY · PI Zachary Reitman · 2022 to 2026
$1.1M
NCI NIH HHS K08 CA256045
6 · The paper itself

Abstract

Background: Diffuse midline gliomas (DMGs) are incurable brain tumors with limited treatment options. Approximately 20% of DMGs harbor truncating mutations in exon 6 of phosphatase Methods: We developed a conditional Results: While Meox2-Cre-driven ubiquitous recombination of Conclusions:

Indexed as

diffuse midline gliomas (DMG)mouse embryonic fibroblasts (MEFs)Ppm1dRCAS/tv-a system

Identifiers

PMID41394550
PMCPMC12697365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.