ArticleBiomedical optics express2025
Near-infrared-II pulsed laser diode array for spectral photoacoustic imaging of deep tissue oxygenation.
Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Optimization of light source parameters for photoacoustic imaging: trade-offs, technologies, and clinical considerations.JPhys photonics · 2026Review
- 3D Measurement of Chronic Wounds in Routine Care: A Review with Practical Guidance for Smartphone Photogrammetry.Annals of biomedical engineering · 2026Review
- Introduction to the feature issue Photoacoustic Imaging and Sensing: Beyond Fundamentals to Translation.Biomedical optics express · 2026Article
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Authors and funding
4 authors.
Funding
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Abstract
Spectral photoacoustic imaging (sPAI) has the potential to detect clinically relevant measurements of blood oxygenation, non-invasively in real time. The unique advantage of sPAI is its ability to probe optical chromophores at extended imaging depths compared to purely optical modalities. PA imaging has previously been demonstrated using benchtop nanosecond pulsed solid-state lasers; however, their size and high cost limit the potential for clinical translation. Microfabricated pulsed laser diodes (PLDs) are miniaturized laser sources that can be fabricated and integrated at relatively low cost; however, microfabricated PLDs have been minimally investigated for the generation of photoacoustic signals due to the significantly lower energies they typically provide. In this work, we integrated an array of PLD diodes with optical excitation in the second near-infrared window, demonstrating deep imaging depths that exceed the imaging depths expected based on fluence alone. Using five PLDs integrated in series at a fluence of 61.5 µJ/cm
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Registered trials
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