Evidence map›Paper›PMID 41394483›Full record

ArticleBiomedical optics express2025

Influence of retinal eccentricity, color blindness, and age on optoretinography measured with AOSLO.

Julia Granier, Elena Gofas Salas, Kate Grieve

Abstract read
In one paragraph

Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. ƒ(Cell): Software for Reproducible Analysis of Optoretinograms.Translational vision science & technology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Julia GranierSorbonne Université, INSERM, CNRS, Institut de la Vision, 17 rue Moreau, F-75012 Paris, France.ORCID https://orcid.org/0009-0008-7372-9149
Elena Gofas SalasSorbonne Université, INSERM, CNRS, Institut de la Vision, 17 rue Moreau, F-75012 Paris, France.ORCID https://orcid.org/0000-0003-1975-0373
Kate GrieveSorbonne Université, INSERM, CNRS, Institut de la Vision, 17 rue Moreau, F-75012 Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optoretinography (ORG) is a recent technique for assessing photoreceptor function by measuring their physiological responses to a flash of light. These responses induce changes in the optical properties of photoreceptors, which can be analyzed to evaluate cone photoreceptor health. Recent studies suggest that ORG could be a useful biomarker for detecting retinal pathologies. However, the ORG signal depends on various non-pathology-related factors that need to be taken into account for effective clinical translation. Here, we introduce a new ORG metric and mapping based on the percentage of cones responsive to the stimulus, and we study the effects of retinal eccentricity, color blindness, and age on intensity-based ORG (iORG) using an adaptive optics scanning laser ophthalmoscope (AOSLO).

Identifiers

PMID41394483
PMCPMC12698108

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.