Evidence map›Paper›PMID 41394460›Full record

ReviewIndian journal of orthopaedics2025

Quadriceps Tendon Graft Leads to Stronger Flexion and Weaker Extension of the Knee Than Hamstring Graft Post-ACLR: Systematic Review and Meta-Analysis.

Brandon A Young, James C Dawahare, Edward Lee Major, Eva L Morrison, Cailan L Feingold, Eric H Lin, Joseph N Liu, Austin V Stone

Erratum issuedAbstract readReview
In one paragraph

Review in Indian journal of orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Brandon A YoungDepartment of Orthopaedic Surgery, University of Kentucky College of Medicine, 740 S Limestone St., Room K423, LexingtonLexington, KY 40508 USA.
James C DawahareDepartment of Orthopaedic Surgery, University of Kentucky College of Medicine, 740 S Limestone St., Room K423, LexingtonLexington, KY 40508 USA.ORCID 0009-0001-9973-2310
Edward Lee MajorDepartment of Orthopaedic Surgery, University of Kentucky College of Medicine, 740 S Limestone St., Room K423, LexingtonLexington, KY 40508 USA.
Eva L MorrisonDepartment of Orthopaedic Surgery, University of Kentucky College of Medicine, 740 S Limestone St., Room K423, LexingtonLexington, KY 40508 USA.
Cailan L FeingoldDepartment of Orthopaedic Surgery, Keck School of Medicine of USC, Los Angeles, CA USA.
Eric H LinDepartment of Orthopaedic Surgery, Keck School of Medicine of USC, Los Angeles, CA USA.
Joseph N LiuDepartment of Orthopaedic Surgery, Keck School of Medicine of USC, Los Angeles, CA USA.
Austin V StoneDepartment of Orthopaedic Surgery, University of Kentucky College of Medicine, 740 S Limestone St., Room K423, LexingtonLexington, KY 40508 USA.

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
NCATS NIH HHS UL1 TR001998
6 · The paper itself

Abstract

Purpose: The optimal autograft for restoring knee strength and expediting return-to-sport following anterior cruciate ligament reconstruction (ACLR) remains debated. This systematic review and meta-analysis compared isokinetic strength and patient-reported outcomes after ACLR using quadriceps tendon (QT), hamstring tendon (HT), or bone-patellar tendon-bone (BTB) autografts to determine graft-specific recovery patterns. Methods: PubMed, Cochrane Library, EMBASE, and Google Scholar were systematically searched for comparative studies evaluating isokinetic strength following primary ACLR using QT, HT, or BTB autografts. Non-English, unavailable full-text, animal/cadaveric, and physeal-sparing studies were excluded. MINORS and Detsky evaluated bias risk. Key findings were quantified, and subgroup meta-analyses were performed on limb symmetry index (LSI) values (significance: Results: Seventeen studies (1,705 patients: QT = 765, HT = 725, BTB = 215) with follow-ups through 48 months were included. Due to data heterogeneity, four to six studies qualified for each meta-analysis. Among 13 QT vs. HT studies, QT grafts demonstrated weaker extensor strength in nine (56.3%) and greater flexor strength in six (37.5%). No differences were reported in extensor or flexor strength in four (25.0%) and seven (43.8%) studies, respectively. For QT vs. BTB, two studies (12.5%) showed similar extensor strength, whereas two reported conflicting results. QT had greater flexor strength in one (6.3%) and similar strength in three (18.8%) studies. Postoperative pain was comparable between QT and HT. Conclusions: QT autografts resulted in stronger flexion and weaker extension than HT autografts after ACLR. Tailored rehabilitation targeting graft-specific deficits may accelerate recovery. Further research is required to clarify outcomes between QT and BTB autografts.

Indexed as

ACL rehabilitationAnterior cruciate ligament reconstructionBone–patellar tendon–bone graftGraft selectionHamstrings tendon graftIsokinetic strengthKnee stabilityPostoperative knee rehabilitationQuadriceps tendon graftReturn-to-sport

Identifiers

PMID41394460
PMCPMC12696245

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.