Evidence map›Paper›PMID 41394442›Full record

Reviewnpj biomedical innovations2025

Immunomodulatory biomaterials for treating chronic inflammation at mucosal sites.

Lauren M Babb, Maria J Kulapurathazhe, Joel H Collier

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in npj biomedical innovations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. [Frontier research on smart delivery biomaterials in the field of oral tissue engineering].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lauren M BabbDepartment of Biomedical Engineering, Duke University, Durham, NC USA.
Maria J KulapurathazheDepartment of Biomedical Engineering, Duke University, Durham, NC USA.
Joel H CollierDepartment of Biomedical Engineering, Duke University, Durham, NC USA.

Funding

Supramolecular biomaterials for tuning the inflammatory properties of the complement systemR01AI172151 · NIAID · DUKE UNIVERSITY · PI COLLIER, JOEL H · 2022 to 2025
$2.8M
Engineered immunotherapies neutralizing interleukin-22 binding proteinR21EB033687 · NIBIB · DUKE UNIVERSITY · PI COLLIER, JOEL H · 2022 to 2023
$435k
NIAID NIH HHS R01 AI172151NIBIB NIH HHS R21 EB033687
6 · The paper itself

Abstract

Biomaterials are increasingly sought as central components of new medical technologies for inflammatory conditions because they serve a range of functions from inert carriers of anti-inflammatory molecules to active engagers of the immune system. Unique challenges presented by diseases of mucosal tissues necessitate biomaterial designs that can circumvent the mucosal barrier and engage tissue-specific immune cells. This review will describe recent advances in biomaterials for treating specific mucosal inflammatory diseases.

Indexed as

Applied immunologyBiomaterials - proteinsBiomedical materialsDrug delivery

Identifiers

PMID41394442
PMCPMC12700820

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.