ArticlePakistan journal of medical sciences2025
Effectiveness of pancreatitis activity score plus coagulation function and serum calcium in predicting the severity and outcome of acute pancreatitis.
Article in Pakistan journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Association between peak D-dimer levels within 24 hours of admission and the risk of infected pancreatic necrosis in hyperlipidemic acute pancreatitis: a retrospective analysis.Frontiers in medicine · 2026Article
- Validation of an Integrated Clinical Biomarker Diagnostic Model for Acute Pancreatitis: Incorporating Trypsinogen-Activating Peptide and Trypsin-2 in a Romanian Population Study.Journal of clinical medicine · 2025Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To examine the relationship between acute pancreatitis (AP) severity and both coagulation function and serum calcium levels. Methods: This is a retrospective study. A total of one hundred patients with AP admitted to our hospital from July 2022 to January 2024. Fifty patients with severe AP(SAP) were assigned to the experimental group, fifty patients with mild-to-moderate AP were assigned to the control group. The pancreatitis activity score system(PASS) score, platelet(PLT) count, von Willebrand factor antigen(vWF:Ag), prothrombin time(PT), activated partial prothrombin time, fibrinogen, thrombin time, antithrombin III(ATIII), plasminogen, serum calcium(Ca) and D-dimer(D-D) were compared. The independent risk factors for predicting AP severity were analysed. The prognostic predictive value and diagnostic efficacy of these independent risk factors were assessed. Results: The experimental group exhibited a statistically significant increase in the PASS score, vWF:Ag, PT and D-D levels and a significant decrease in PLT, ATIII and Ca levels compared with the control group(P< 0.001). Logistic regression analysis showed that PASS, vWF:Ag, PT, ATIII, D-D and Ca were independent risk factors for predicting the severity of AP; Ca levels had the highest diagnostic efficacy, followed by ATIII and PT; vWF:Ag was the least effective. The levels of vWF:Ag, PT, and D-D are positively correlated with PASS scores, the levels of ATIII and Ca are negatively correlated. Conclusion: The levels of vWF:Ag, PT, D-D, ATIII, and Ca in AP patients are correlated with the severity of the condition, and Ca levels may more accurately and early assess the severity of AP patients.
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