ArticlePakistan journal of medical sciences2025
Clinical efficacy of antibacterial drugs combined with Proton Pump Inhibitors and Bismuth in the treatment of Helicobacter Pylori-infected Peptic Ulcer.
Article in Pakistan journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the clinical efficacy of antibacterial drugs combined with proton pump inhibitors and bismuth in the treatment of Helicobacter pylori (Hp)-infected peptic ulcer. Methodology: This was a retrospective study. A total of 116 patients with Hp-infected peptic ulcer treated at Cangzhou People's Hospital from January 2023 to December 2024 were selected as study subjects and randomly divided into an observation group(n=58) treated with antibacterial drugs in addition to the treatment for the control group and a control group(n=58) received proton pump inhibitors and bismuth using the computer-based lottery method. The clinical efficacy, time to symptom subsidence treatment safety were assessed and compared between the two groups. Results: The overall response rate of the observation group was higher than that of the control group( Conclusion: Antibacterial drugs combined with proton pump inhibitors and bismuth are remarkably effective in treating Hp-infected peptic ulcer, which promotes the subsidence of symptoms, improves gastric function, increases gastrointestinal hormone levels.
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