ArticlePakistan journal of medical sciences2025
Feasibility analysis of pharmacy practice based on the evidence-based pharmacy model in the treatment of patients with severe pneumonia.
Article in Pakistan journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the application of pharmacy practice based on the evidence-based pharmacy (EBP) model in the anti-infective treatment of patients with severe pneumonia. Methodology: This was a retrospective study. A total of 200 patients diagnosed with severe pneumonia caused by multidrug-resistant Gram-negative bacilli(MDR-GNB) and admitted to Baoding No.1 Central Hospital from April 2023 to March 2024 were randomly assigned to a control group(received conventional anti-infective treatment) and an experimental group(in addition to the conventional treatment, received pharmacy practice interventions based on the EBP model implemented by clinical pharmacists), with one hundred cases in each group.The two groups were compared in terms of antimicrobial drug use intensity, pre-antibiotic microbiological testing rates, clinical efficacy, adverse reaction rates, and irrational drug use. Results: The antimicrobial drug use intensity in the experimental group was significantly lower than that in the control group ( Conclusion: EBP model-based pharmacy practice may assist physicians in optimizing anti-infective treatment regimens for patients with severe pneumonia caused by MDR-GNB, improving treatment outcomes and medication safety while effectively enhancing patient prognosis.
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