Evidence map›Paper›PMID 41394293›Full record

Trial reportBioMed research international2025

Healing Oral Mucositis With

Núbia de Cássia Almeida Queiroz, Ilza Maria de Oliveira Sousa, Rogério José Machado Júnior, Afonso Celso Vigorito, Elida Adriana de Castro Aranha, Andressa Gomes Melo, João Ernesto de Carvalho, Mary Ann Foglio

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BioMed research international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Healing Oral Mucositis WithBioMed research international · 2025
    Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Núbia de Cássia Almeida QueirozFaculty of Medical Sciences, State University of Campinas, Sao Paulo, Brazil, unicamp.br.ORCID https://orcid.org/0000-0003-1510-5684
Ilza Maria de Oliveira SousaFaculty of Pharmaceutical Sciences, State University of Campinas, Sao Paulo, Brazil, unicamp.br.ORCID https://orcid.org/0000-0002-3956-3199
Rogério José Machado JúniorFaculty of Medical Sciences, State University of Campinas, Sao Paulo, Brazil, unicamp.br.
Afonso Celso VigoritoFaculty of Medical Sciences, State University of Campinas, Sao Paulo, Brazil, unicamp.br.ORCID https://orcid.org/0000-0002-9990-1313
Elida Adriana de Castro AranhaFaculty of Medical Sciences, State University of Campinas, Sao Paulo, Brazil, unicamp.br.
Andressa Gomes MeloFaculty of Medical Sciences, State University of Campinas, Sao Paulo, Brazil, unicamp.br.ORCID https://orcid.org/0000-0003-2645-1937
João Ernesto de CarvalhoFaculty of Pharmaceutical Sciences, State University of Campinas, Sao Paulo, Brazil, unicamp.br.ORCID https://orcid.org/0000-0002-6901-6815
Mary Ann FoglioFaculty of Pharmaceutical Sciences, State University of Campinas, Sao Paulo, Brazil, unicamp.br.ORCID https://orcid.org/0009-0008-5478-0977

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Oral mucositis affects up to 80% of patients undergoing bone marrow transplantation, causing painful ulcers, increased infection risk, and impaired quality of life. Current treatments are mainly palliative, highlighting the need for new therapeutic options. Objective: The objective of the study is to evaluate the wound healing potential of a mucoadhesive gel containing 2.5% Methods: This was a randomized, controlled, open-label, parallel-group clinical trial conducted at HC/UNICAMP from October 2022 to November 2024. Forty-four patients were randomized to the intervention group (mucoadhesive Results: Twenty participants in the intervention group and 18 in the control group completed the study. Mean healing time was 5.2 ± 1.5 days for the intervention group and 11.2 ± 6.5 days for the control group, representing a 2.2-fold faster healing with Conclusion: The mucoadhesive gel containing Trial Registration: ReBEC number: RBR-5×4397.

Indexed as

FabaceaeHematopoietic Stem Cell TransplantationPlant ExtractsStomatitisWound HealingAdultFemaleGelsHumansMaleMiddle AgedGelsPlant ExtractsArrabidaea chicaFridericia chicahealingoral mucositis

Identifiers

PMID41394293
PMCPMC12699320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.