Evidence map›Paper›PMID 41394292›Full record

ArticleBioMed research international2025

Antitumor Effects of Chemlali and Wild Olive Tree Extracts: Role in Cell Proliferation and Apoptosis in Prostate (PC3) and Breast (MDA-MB-231) Cancer Cell Lines.

Radhia Bouazizi, Lamjed Bouslama, Fatma Nouira, Alice Grossi, Mattia De Vita, Bechir Baccouri, Selim Jallouli, Samantha Solito, Monica Savio, Virginie Sottile and 1 more

Abstract read
In one paragraph

Article in BioMed research international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Radhia BouaziziLaboratory of Biotechnology of Olive, Centre of Biotechnology of Borj Cedria, Hammam-Lif, Tunisia.ORCID https://orcid.org/0009-0002-6211-2190
Lamjed BouslamaLaboratory of Bioactive Substances, Centre of Biotechnology of Borj Cedria, Hammam-Lif, Tunisia.ORCID https://orcid.org/0000-0002-2969-8639
Fatma NouiraLaboratory of Bioactive Substances, Centre of Biotechnology of Borj Cedria, Hammam-Lif, Tunisia.ORCID https://orcid.org/0000-0001-6589-9000
Alice GrossiDepartment of Molecular Medicine, Immunology and General Pathology Unit, University of Pavia, Pavia, Italy, unipv.eu.ORCID https://orcid.org/0009-0007-8712-918X
Mattia De VitaDepartment of Molecular Medicine, Immunology and General Pathology Unit, University of Pavia, Pavia, Italy, unipv.eu.ORCID https://orcid.org/0009-0007-8607-1510
Bechir BaccouriLaboratory of Biotechnology of Olive, Centre of Biotechnology of Borj Cedria, Hammam-Lif, Tunisia.ORCID https://orcid.org/0000-0003-1920-8277
Selim JallouliLaboratory of Bioactive Substances, Centre of Biotechnology of Borj Cedria, Hammam-Lif, Tunisia.ORCID https://orcid.org/0000-0003-1751-4393
Samantha SolitoCentro Grandi Strumenti (CGS), University of Pavia, Pavia, Italy, unipv.eu.ORCID https://orcid.org/0000-0003-2544-1673
Monica SavioDepartment of Molecular Medicine, Immunology and General Pathology Unit, University of Pavia, Pavia, Italy, unipv.eu.ORCID https://orcid.org/0000-0003-0437-7027
Virginie SottileDepartment of Molecular Medicine, Immunology and General Pathology Unit, University of Pavia, Pavia, Italy, unipv.eu.ORCID https://orcid.org/0000-0002-6064-5738
Leila AbazaLaboratory of Biotechnology of Olive, Centre of Biotechnology of Borj Cedria, Hammam-Lif, Tunisia.ORCID https://orcid.org/0000-0001-9950-1478

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer remains a major global health challenge, requiring natural therapeutic solutions. Olive tree by-products, like leaves and pomace, are rich in bioactive phenolics with antioxidant and anticancer potential. This study explores the chemical composition and anticancer potential of the hexane fraction of olive leaf extracts and the dichloromethane fraction of olive pomace extracts from two

Indexed as

ApoptosisBreast NeoplasmsCell ProliferationOleaPlant ExtractsProstatic NeoplasmsCell Line, TumorFemaleHumansMalePC-3 CellsPlant LeavesPlant Extractsantitumoral activityapoptosisbreast cancer (MDA-MB-231)olive leafolive pomaceprostate cancer (PC3)

Identifiers

PMID41394292
PMCPMC12699138

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.