ArticleClinical medicine insights. Endocrinology and diabetes2025
Association Between Abdominal Obesity and Hyperuricemia in Peruvian Adults with Type 2 Diabetes Mellitus.
Article in Clinical medicine insights. Endocrinology and diabetes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and risk factors of hyperuricemia and gout in patients with type 2 diabetes mellitus: a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
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6 authors.
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Abstract
Background: Abdominal obesity (AO) is associated with hyperuricemia (HU) in people with type 2 diabetes (T2DM), but most evidence comes from Asian studies and Latin American data are scarce. This study addresses that gap in a Peruvian setting. We aimed to evaluate the association between AO and HU in adult Peruvians diagnosed with T2DM. Methods: We carried out a cross-sectional observational study in adults with T2DM in a private clinic in Lima - Peru. We defined HU as serum uric acid ⩾ 6 mg/dL and defined AO as waist circumference ⩾ 94 cm in men and ⩾88 cm in women. In addition, we estimated crude and adjusted prevalence ratios (PRs) with 95% CIs for the AO-HU association, adjusting for sex, glycosylated hemoglobin, estimated glomerular filtration rate, and systolic/diastolic blood pressure. Results: We evaluated 815 adults with T2DM. 62.6% were male, and the average age was 57 years. AO was present in 82.9% and HU in 22.7%. The prevalence of HU in adults with AO was 24.3%, while the prevalence was 15.1% in those not obese. AO was associated with HU in the crude analysis (cPR: 1.60 95% CI 1.05-2.43) and remained statistically significant after adjustment for sex, glycosylated hemoglobin, estimated glomerular filtration rate, and systolic/diastolic blood pressure (aPR: 1.95 95% CI 1.31-2.90). Conclusion: In Peruvian adults with T2DM, abdominal obesity was associated with nearly double the prevalence of hyperuricemia. Because waist circumference is simple and low-cost to measure, integrating it into routine diabetes visits, along with targeted uric acid screening and management, may enhance cardiometabolic risk stratification and guide timely interventions.
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