Evidence map›Paper›PMID 41394119›Full record

ArticleJournal of cellular signaling2025

Signaling of Mitogenic and Metabolic Activities by Fibroblast Growth Factors.

Patience Salvalina Okoto, Zeina Alraawi, Thallapuranam Krishnaswamy Suresh Kumar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cellular signaling, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Patience Salvalina OkotoDepartment of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR 72701, USA.
Zeina AlraawiDepartment of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR 72701, USA.
Thallapuranam Krishnaswamy Suresh KumarDepartment of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR 72701, USA.

Funding

Center for Protein Structure and FunctionP30GM103450 · NIGMS · UNIVERSITY OF ARKANSAS AT FAYETTEVILLE · PI MILLETT, FRANCIS S · 2012 to 2014
$3.2M
Biopolymer-based strategies for local delivery of cytokine therapeuticsR01CA172631 · NCI · UNIVERSITY OF ARKANSAS AT FAYETTEVILLE · PI ZAHAROFF, DAVID · 2014 to 2018
$1.5M
Hyperstable FGF1-FGF2 based therapeutic formulation for wound careR15GM154267 · NIGMS · UNIVERSITY OF ARKANSAS AT FAYETTEVILLE · PI THALLAPURANAM, SURESH KUMAR KRISHNASWAMY · 2024 to 2024
$435k
NCI NIH HHS R01 CA172631NIGMS NIH HHS P30 GM103450NIGMS NIH HHS R15 GM154267
6 · The paper itself

Abstract

Fibroblast growth factors are signaling molecules that play crucial roles in fundamental processes such as cell migration, proliferation, differentiation, angiogenesis, and cell survival. FGFs signal by forming a complex with tyrosine kinase FGF receptors and cofactors. It is well known that FGFs play diverse roles in different tissues and at different developmental stages due to factors such as receptors, specific FGFs, and environmental conditions such as temperature and pH. This review focuses on the actions of mitogenic and metabolic FGFs and their interactions with their receptors to trigger their designated functions.

Indexed as

Cell signalingFibroblast growth factorsMetabolic FGFsMitogenic FGFs

Identifiers

PMID41394119
PMCPMC12700623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.