Evidence map›Paper›PMID 41393983›Full record

ReviewJournal of the Canadian Association of Gastroenterology2025

Recommendations for the diagnosis and management of eosinophilic esophagitis in adults and children in Canada: a Delphi consensus project.

Vishal Avinashi, Milli Gupta, Beth A Payne, Haneen Amhaz, Alisha T Temirova, Waqqas Afif, Dhandapani Ashok, Janice Barkey, David Burnett, Jonathan W Bush and 24 more

Abstract readReview
In one paragraph

Review in Journal of the Canadian Association of Gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Vishal AvinashiDivision of Gastroenterology, Hepatology and Nutrition, BC Children's Hospital, Department of Pediatrics, University of British Columbia, V6H 3V4, Canada.
Milli GuptaDivisions of Gastroenterology and Hepatology, Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, T2N 4Z6, Canada.
Beth A PayneWomen's Health Research Institute, BC Children's Hospital Research Institute, Simon Fraser University School of Medicine, V5A 1S6, Canada.ORCID https://orcid.org/0000-0001-6150-8703
Haneen AmhazInstitute for Global Health, BC Children's Hospital Research Institute, Provincial Health Services Authority, V5Z 2X8, Canada.
Alisha T TemirovaBC Children's Hospital Research Institute, V5Z 2X8, Canada.
Waqqas AfifDivision of Gastroenterology and Hepatology, McGill University Health Center, McGill University, H4A 3J1, Canada.
Dhandapani AshokDivision of Pediatric Gastroenterology, Hepatology & Nutrition, Department of Pediatrics, Western University, London, Ontario, N6A 5W9, Canada.
Janice BarkeyDivision of Pediatric Gastroenterology, Hepatology & Nutrition, Department of Pediatrics, University of Ottawa, CHEO, Ottawa, Ontario, K1H 8L1, Canada.
David BurnettDivision of Pediatric Gastroenterology and Nutrition, Department of Pediatrics, Dalhousie University, B3K 6R8, Canada.
Jonathan W BushDepartment of Pathology and Laboratory Medicine, University of British Columbia, BC Children's and Women's Hospital, V6H 3V4, Canada.ORCID https://orcid.org/0000-0001-9432-2390
Scott CameronDivision of Allergy & Immunology, Department of Pediatrics, University of British Columbia, V6H 3N1, Canada.
Stuart CarrSnö Asthma & Allergy, Abu Dhabi, Abu Dhabi, United Arab Emirates.
Dina El DemellawyDepartment of Pathology, University of Ottawa Ontario, K1Y 4E9, Canada.
Stephanie ErdleDivision of Allergy, Department of Pediatrics, University of British Columbia, BC Children's Hospital, Vancouver, British Columbia, V6H 3N1, Canada.
Hien Q HuynhDivision of Pediatric GI Nutrition, Department of Pediatrics, Stollery Children's Hospital, University of Alberta, Edmonton Clinic Health Academy (ECHA), Edmonton, Alberta, T6G 1C9, Canada.ORCID https://orcid.org/0000-0002-7295-7595
Jennifer GriffinDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Winnipeg Children's Hospital, Department of Pediatrics, University of Manitoba, R3A 1S1, Canada.
Samir C GroverDivision of Gastroenterology, Scarborough Health Network Research Institute, University of Toronto, Toronto, M1P 2V5, Canada.
Kelly GrzywaczDivision of Pediatric Gastroenterology Hepatology and Nutrition, CHU Sainte Justine, H3T 1C5, Canada.
Samira JeimyDivision of Clinical Immunology and Allergy, Department of Medicine, Western University, Lawson Health Research Institute, London, Ontario, N6A 4V2, Canada.
Hin Hin KoDivision of Gastroenterology & Hepatology, Department of Medicine, St. Paul' s Hospital, University of British Columbia, V6Z 1Y6, Canada.
Gina LacuestaDepartment of Medicine, Dalhousie University, Halifax Allergy and Asthma Associates, B3H 1X5, Canada.
Margaret MarconHospital for Sick Children, Department of Pediatrics, University of Toronto, Toronto, Ontario, M5G 1X8, Canada.
Serge MayrandDivision of Gastroenterology and Hepatology, McGill University Health Center, McGill University, H4A 3J1, Canada.
Harrison PetropolisDepartment of Medicine, Division of Digestive Care & Endoscopy, Dalhousie University, B3H 4R2, Canada.
David RodriguesDivision of Gastroenterology, Queen's University, K7L 2V7, Canada.
Mary SherlockDepartment of Pediatrics, McMaster University, Division of Pediatric Gastroenterology, McMaster Children's Hospital, L8L 0A4, Canada.
Christine SongUniversity of Toronto, St Michael's Hospital, Sunnybrook Health Sciences Centre, M5B 1W8, Canada.
Natacha TardioAdult Clinical Immunology and Allergy, McGill University Health Centre, H4A 3J1, Canada.
Timothy K Vander LeekPediatric Allergy & Clinical Immunology, Department of Pediatrics, University of Alberta, T6G 1C9, Canada.
Meagan VurzingerDivision of Gastroenterology, Hepatology and Nutrition, BC Children's Hospital, Department of Pediatrics, University of British Columbia, V6H 3V4, Canada.
Brock WilliamsDivision of Allergy, Department of Pediatrics, The University of British Columbia, BC Children's Hospital Research Institute, V6H 3V4, Canada.ORCID https://orcid.org/0000-0003-3239-2697
Ted XenodemetroupolousDepartment of Medicine, Division of Gastroenterology and Division of Education and Innovation, McMaster University and Hamilton Health Sciences, L8N 3Z5, Canada.
Christopher MaDivision of Gastroenterology & Hepatology, Departments of Medicine & Community Health Sciences, University of Calgary, T2N 4Z6, Canada.ORCID https://orcid.org/0000-0002-4698-9948
Edmond S ChanDivision of Allergy, Department of Pediatrics, University of British Columbia, BC Children's Hospital, Vancouver, British Columbia, V6H 3N1, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus that effects both pediatrics and adult patients in Canada and is increasing in prevalence. No Canadian focused best practice recommendations currently exist to guide clinical practice. Methods: The study used a modified Delphi technique to develop evidence and expert opinion-based recommendations for providing care for patients with EoE. The Delphi process consisted of 3 rounds of quantitative surveys and qualitative consensus meetings. Experts were included in the Delphi if they had experience caring for EoE patients in Canada within one of the following professional groups: allergist, adult gastroenterologists, pathologists, pediatric gastroenterologists, and dieticians. Results: Delphi rounds were completed between May 1, 2024, and June 30, 2024. A total of 31 experts in EoE care from across Canada were recruited to participate in the Delphi consensus process. All participants completed all 3 rounds of Delphi surveys. The final statement includes 38 recommendations for the care of patients with EoE organized into 3 sections: definition, diagnosis, and management. A table of research gaps is provided to stimulate further knowledge development on this topic. Conclusion: This consensus statement includes actionable recommendations to support quality care of patients with EoE at any age across Canada. We encourage EoE centres in Canada to come together in a multidisciplinary form to not only provide clinical care but also do much needed research on Canadian specific topics and gaps in EoE care.

Indexed as

consensusDelphiEoEeosinophilic esophagitisguideline

Identifiers

PMID41393983
PMCPMC12698229

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.