ReviewFrontiers in nutrition2025
Plant-based dietary miRNAS: cross-border regulatory factors for regulating glycolipid metabolism and their nutritional intervention strategies.
Review in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Disorders of glucose and lipid metabolism represent a major global health burden, driving the need for innovative nutritional interventions. Emerging evidence suggests that dietary microRNAs (miRNAs) from plants can act as cross-kingdom regulators. These molecules may survive digestion, enter the mammalian circulation, and modulate host gene expression to influence glycolipid homeostasis. This review comprehensively synthesizes current knowledge in this field, beginning with the dietary origins of plant miRNAs and evaluating their stability during food processing and gastrointestinal passage. We critically examine the mechanisms and ongoing debates regarding their absorption, transport, and biodistribution. The review further elucidates how specific plant miRNAs target key genes and signaling pathways involved in glucose and lipid metabolism, while also exploring their interplay with gut microbiota and metabolic inflammation. We summarize supporting evidence from
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.