Evidence map›Paper›PMID 41393937›Full record

SynthesisFrontiers in nutrition2025

Early nurse-initiated enteral nutrition and its impact on postoperative recovery and complication rates: a meta-analysis of surgical patient outcomes.

Biao Shi, Lan Shen, Zhengying Xu, Binhua Yu, Xiao Yang, Hongcui Yang, Chaoming Chen

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Biao ShiDepartment of Emergency, Dali Bai Autonomous Prefecture People's Hospital, Dali, China.
Lan ShenSouthern Central Hospital of Yunnan Province, The First People's Hospital of Honghe State, Gejiu, China.
Zhengying XuDepartment of Emergency, Dali Bai Autonomous Prefecture People's Hospital, Dali, China.
Binhua YuDepartment of Emergency, Dali Bai Autonomous Prefecture People's Hospital, Dali, China.
Xiao YangDepartment of Emergency, Dali Bai Autonomous Prefecture People's Hospital, Dali, China.
Hongcui YangDepartment of Emergency, Dali Bai Autonomous Prefecture People's Hospital, Dali, China.
Chaoming ChenSouthern Central Hospital of Yunnan Province, The First People's Hospital of Honghe State, Gejiu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Nutritional support after surgery is an essential part of recovery augmentation protocols, especially in high-risk surgical patients. Early enteral nutrition (EEN) within 24-48 h after surgery has been argued to enhance gastrointestinal function, decrease complications, and minimize hospital stay. The purpose of this research was to provide clinical study evidence synthesis on the effect of EEN on postoperative recovery and complication rates for varying surgical patient populations. Methodology: 30 clinical trials, with 1996-2023 information, of 2,432 patients undergoing surgery, equally divided into early enteral/oral nutrition (EEN) and standard enteral/oral nutrition (SEN) groups, were compared. The randomized controlled trials (RCTs), prospective and retrospective cohort designs, as well as observational analysis studies, comprised the studies. Populations included neonates, pediatric cardiovascular patients, adults with gastrointestinal, oncologic, and emergency abdominal surgery. Sample size, type of intervention, duration, outcomes, and complications were extracted data. Results: EEN was linked with shorter hospital stay, earlier return of bowel function, better weight gain, increased immune and nutritional status, and reduced rates of postoperative complications, especially infections. Adverse events like anastomotic leaks or feeding intolerance were not significantly increased. Most RCTs proved to have significant advantages in early initiation of feeding over traditional delayed protocols. Conclusion: Early enteral nutrition is a safe and effective method for optimizing postoperative recovery in a wide range of surgical patients. It profoundly improves clinical results without raising the risk of complications. These results justify the incorporation of EEN into routine postoperative care pathways.

Indexed as

clinical trialsearly enteral nutritionearly oral feedingenhanced recoverygastrointestinal surgerypediatric cardiac surgerypostoperative recoverysurgical complications

Identifiers

PMID41393937
PMCPMC12695597

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.