Evidence map›Paper›PMID 41393811›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

The Rapid Naming Test: Neuroanatomical validity and clinical utility.

Kelly J Atkins, Samhita Katteri, Alexandra J Weigand, Jordan Stiver, Leslie S Gaynor, Elena Tsoy, Sabrina J Erlhoff, Katherine Rankin, Maria Luisa Mandelli, Maria Luisa Gorno-Tempini and 2 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Rapid Naming Test: Neuroanatomical validity and clinical utility.Alzheimer's & dementia (Amsterdam, Netherlands)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kelly J AtkinsMemory and Aging Center, UCSF Weill Institute for Neurosciences University of California San Francisco San Francisco California USA.
Samhita KatteriMemory and Aging Center, UCSF Weill Institute for Neurosciences University of California San Francisco San Francisco California USA.
Alexandra J WeigandMemory and Aging Center, UCSF Weill Institute for Neurosciences University of California San Francisco San Francisco California USA.
Jordan StiverDepartment of Neurosciences University of California San Diego San Diego California USA.
Leslie S GaynorDivision of Geriatric Medicine Department of Medicine Vanderbilt University Medical Center Nashville Tennessee USA.
Elena TsoyMemory and Aging Center, UCSF Weill Institute for Neurosciences University of California San Francisco San Francisco California USA.
Sabrina J ErlhoffMemory and Aging Center, UCSF Weill Institute for Neurosciences University of California San Francisco San Francisco California USA.
Katherine RankinMemory and Aging Center, UCSF Weill Institute for Neurosciences University of California San Francisco San Francisco California USA.
Maria Luisa MandelliMemory and Aging Center, UCSF Weill Institute for Neurosciences University of California San Francisco San Francisco California USA.
Maria Luisa Gorno-TempiniMemory and Aging Center, UCSF Weill Institute for Neurosciences University of California San Francisco San Francisco California USA.
Joel H KramerMemory and Aging Center, UCSF Weill Institute for Neurosciences University of California San Francisco San Francisco California USA.
Katherine L PossinMemory and Aging Center, UCSF Weill Institute for Neurosciences University of California San Francisco San Francisco California USA.

Funding

TDP-43 Loss-of-Function: Biology to BiomarkersP01AG019724 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Jennifer Merrilees · 2002 to 2026
$67.2M
Research Education ComponentP30AG062422 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Gil Dan Rabinovici · 2019 to 2026
$36.9M
Augmenting Nurse Support and EHR Integration for the Pragmatic Trial of the UCSF-BHAU01NS128913 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Katherine Laurel Possin · 2022 to 2026
$8.2M
Reimagining Precision Medicine Approaches to AD DiagnosisR35AG072362 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI POSSIN, KATHERINE LAUREL, RABINOVICI, GIL DAN · 2021 to 2025
$4.8M
NIA NIH HHS P01 AG019724NIA NIH HHS P30 AG062422NIA NIH HHS R35 AG072362NINDS NIH HHS U01 NS128913
6 · The paper itself

Abstract

introductionThe Rapid Naming Test (RNT) is a tablet-administered confrontation naming task. We evaluated its concurrent validity, neuroanatomical correlates, sensitivity to cognitive impairment, and discriminant validity across neurodegenerative syndromes.

methodsWe compared RNT performance of 263 healthy adults (mean [SD] age = 73.6 [9.3]; 60.5% female) and 185 people with neurodegenerative syndromes (mean [SD] age = 68.3 [9.0]; 38.9% female), including primary progressive aphasias (PPA). RNT performance were correlated with traditional cognitive test performance and with regional gray matter volumes using voxel-based morphometry.

resultsRNT performance was associated with language, memory, executive function, and processing speed ( DISCUSSION: The RNT is sensitive to cognitive impairment and associated with brain regions involved in language and cognitive control, with left hemisphere predominance. Highlights: The Rapid Naming Test (RNT) is a 1-min tablet-based confrontation naming task.The pattern of performance across clinical cohorts supports the construct validity of the RNT.RNT performance was associated with gray matter volumes in regions important for object recognition and semantic knowledge.Age adjusted norms of the RNT were sensitive to mild cognitive impairment.

Indexed as

dementiadigital assessmentlanguageneuroimagingneuropsychology

Identifiers

PMID41393811
PMCPMC12701363

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.