Evidence map›Paper›PMID 41393809›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Incident traumatic experiences and poor financial well-being: A double hit for cognitive decline?

Katrina L Kezios, Junxian Liu, Audrey R Murchland, Adina Zeki Al Hazzouri, Allison E Aiello, Karestan Koenen, Eleanor Hayes-Larson

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katrina L KeziosDepartment of Epidemiology Mailman School of Public Health Columbia University New York New York USA.ORCID https://orcid.org/0000-0001-7115-032X
Junxian LiuLeonard Davis School of Gerontology University of Southern California Los Angeles California USA.
Audrey R MurchlandDepartment of Epidemiology Boston University School of Public Health Boston Massachusetts USA.
Adina Zeki Al HazzouriDepartment of Epidemiology Mailman School of Public Health Columbia University New York New York USA.
Allison E AielloDepartment of Epidemiology Mailman School of Public Health Columbia University New York New York USA.
Karestan KoenenDepartment of Epidemiology Harvard T.H. Chan School of Public Health Boston Massachusetts USA.
Eleanor Hayes-LarsonLeonard Davis School of Gerontology University of Southern California Los Angeles California USA.

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Expanding the RAND HRS Data System to Better Support Research on Health and AgingR01AG073289 · NIA · RAND CORPORATION · PI SUSANN ROHWEDDER, DAVID R. WEIR · 2022 to 2026
$3.7M
Hypertension, Blood Pressure Targets, and Alzheimer’s Disease and Dementia Risk and Disparities among Nationally Representative US VeteransR01AG085481 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Nestor Sebastian Calonico, Kristine Yaffe · 2024 to 2026
$2.4M
Effects of lifecourse traumatic stress on late-life cognitive decline, dementia, and neuroimaging biomarkersR00AG075317 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Eleanor Louise Hayes-Larson · 2024 to 2026
$742k
Investigating financial wellbeing, biological aging, and risk of Alzheimers disease and related dementias in a life course synthetic cohortR00AG084769 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Katrina L Kezios · 2025 to 2026
$489k
Investigating financial wellbeing, biological aging, and risk of Alzheimers disease and related dementias in a life course synthetic cohortK99AG084769 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KEZIOS, KATRINA L · 2024 to 2025
$263k
NIA NIH HHS K99 AG084769NIA NIH HHS R00 AG075317NIA NIH HHS R00 AG084769NIA NIH HHS R01 AG073289NIA NIH HHS R01 AG085481NIA NIH HHS U01 AG009740
6 · The paper itself

Abstract

introductionTraumatic experiences in older age may accelerate cognitive decline, especially when experienced alongside financial hardship.

methodsIn data from the Health and Retirement Study (2006-2020), we estimated linear mixed-effects models stratified by financial well-being to estimate the effect of incident traumatic experiences on memory decline, adjusted for childhood and adulthood sociodemographics.

resultsIn DISCUSSION: The cognitive impacts of incident traumatic events may be stronger for individuals with poor financial well-being. Future research should confirm our findings and evaluate underlying mechanisms. Highlights: Experiencing an incident trauma in older age predicted accelerated memory decline.This association was strongest for participants with worse financial well-being.Experiencing trauma alongside scarcity may be a double-hit for cognitive decline.

Indexed as

cognitive declineeffect modificationfinancial well‐beingincident traumatic experiencelifetime traumas indextraumatic event

Identifiers

PMID41393809
PMCPMC12696043

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.