Evidence map›Paper›PMID 41393745›Full record

ArticleCureus2025

Obesity and Quality of Life in Young Women: Role of General and Central Adiposity.

Carolina Piterschi, Lorina Vudu

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Carolina PiterschiDepartment of Endocrinology, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, MDA.
Lorina VuduDepartment of Endocrinology, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, MDA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionObesity is a multifaceted disease and a growing public health concern that affects both physical health and psychosocial well-being. While its consequences are well documented in older adults, the impact of obesity on health-related quality of life (HRQoL) in young women remains insufficiently explored. Furthermore, limited evidence is available comparing how general and central adiposity differentially influence the various dimensions of HRQoL. Therefore, this study aimed to assess the impact of obesity on HRQoL in young women by comparing general adiposity and central adiposity across the physical, psychological, and social domains.

methodsA cross-sectional study was conducted among 130 Caucasian women aged 18-45 years (mean age 31.8 ± 6.8 years); 69 with obesity (body mass index (BMI) ≥30 kg/m²) and 61 with normal weight (BMI 18.5-24.9 kg/m²). Anthropometric parameters were recorded, including BMI as an indicator of general adiposity and waist-to-height ratio (WHtR) and waist-to-hip ratio (WHR) as measures of central adiposity. HRQoL was assessed using the 36-Item Short Form Health Survey (SF-36), which evaluates eight domains and two composite scores: the Physical Component Summary (PCS) and Mental Component Summary (MCS).

resultsWomen with obesity reported significantly lower HRQoL across all SF-36 domains compared with normal-weight participants (all p < 0.001). PCS and MCS scores declined progressively with increasing BMI, WHtR, and WHR, with the greatest impairments observed in class II and III obesity and in women with WHtR ≥0.60 or WHR ≥0.86. Correlation and regression analyses confirmed strong inverse associations between adiposity indicators and HRQoL, with central measures emerging as the most sensitive predictors.

conclusionsObesity in young women is associated with marked reductions in HRQoL across both physical and mental domains. The decline was most pronounced in women with class II and III obesity and elevated WHtR and WHR, reflecting the combined effects of general and central adiposity. These findings emphasize the need for early, multidisciplinary interventions targeting abdominal fat reduction and psychosocial well-being to enhance overall quality of life.

Indexed as

body mass indexhealth-related quality of lifewaist-to-height ratiowaist-to-hip ratioyoung women living with obesity

Identifiers

PMID41393745
PMCPMC12701537

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.