ArticleCureus2025
Warthin's Tumor Involved by Monoclonal B-Cell Lymphocytosis: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Warthin's tumor is a benign salivary gland neoplasm characterized by oncocytic epithelium and lymphoid stroma. We describe the incidental discovery of a CD5-positive monoclonal B-cell population within a classic Warthin's tumor of the parotid gland in a 72-year-old woman who presented with a painless, slow-growing left parotid mass. Core needle biopsy and subsequent parotidectomy demonstrated typical histologic features of Warthin's tumor along with a low-level (8%-9%) CD5- and CD23-positive B-cell population consistent with chronic lymphocytic leukemia (CLL)-type monoclonal B-cell lymphocytosis (MBL). No morphologic evidence of overt lymphoma was present, and both CLL fluorescence in situ hybridization (FISH) testing and PET-CT imaging were unremarkable. The patient remains asymptomatic and is currently monitored without therapy. This case illustrates the occurrence of CLL-type MBL within the lymphoid stroma of a Warthin's tumor, emphasizing the importance of careful histologic and immunophenotypic evaluation and the need for clearly defined diagnostic criteria for extranodal tissue-based MBL.
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