ArticleCureus2025
Efficacy of Standard Biophysical Tests in Assessing Fetal Oxygenation Status.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTimely recognition of fetal oxygenation disorders is essential to prevent irreversible injury. Cardiotocography (CTG) and biophysical profile (BPP) are widely used for fetal surveillance, yet their diagnostic and predictive performance relative to umbilical artery (UA) pH and neonatal outcomes warrants further evaluation. This study assessed the efficacy of CTG and BPP in predicting fetal acidosis and a low one-minute Apgar score (AS) and examined their value for identifying fetal hypoxia and asphyxia. MATERIAL AND
methodsWe conducted a retrospective study of 119 hospitalized pregnant women at the Department of Perinatology, University Clinical Center of the Republic of Srpska in Banja Luka, with gestational age ≥ 27 weeks, singleton pregnancies, and no fetal malformations. CTG tracings were classified as normal, equivocal, or pathological. The BPP was scored (0-10) and categorized as normal, equivocal, or pathological. We correlated test results with UA pH (acidosis < 7.20; pre-acidosis 7.20-7.24; normal ≥ 7.25) and the one-minute AS. We calculated sensitivity, specificity, positive predictive value, negative predictive value, and accuracy, and used appropriate significance tests.
resultsCTG and BPP showed similar predictive performance for detecting acidosis and a low one-minute AS. Both methods demonstrated statistically significant associations with UA pH and AS (p < 0.001). Perinatal mortality was 1.68% and morbidity was 24.37%; fatal outcomes were associated with pathological findings on both tests, acidosis, and a low AS.
conclusionCTG and BPP are useful predictors of fetal hypoxia and asphyxia. Integrated use and careful interpretation of both tests can aid in identifying compromised fetuses and guiding timely decisions about the mode and timing of delivery, with the potential to reduce adverse perinatal outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.