ArticleCureus2025
Hemophagocytic Lymphohistiocytosis Associated With Disseminated Histoplasmosis in a Patient With Chronic Pancytopenia: A Rare Case.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Hemophagocytic lymphohistiocytosis (HLH) is an uncommon yet life-threatening immune disorder in which dysregulated activity of cytotoxic T cells and macrophages leads to excessive cytokine release, uncontrolled inflammation, and damage to multiple organ systems. Secondary forms of HLH may develop in response to infections, malignancies, or autoimmune conditions. We present the case of an 80-year-old woman with longstanding pancytopenia who developed disseminated histoplasmosis complicated by HLH. This report highlights the diagnostic difficulties of HLH in older patients and stresses the importance of recognizing this syndrome promptly when opportunistic infections are suspected.
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