ArticleCureus2025
Effects of Non-surgical Periodontal Therapy on Porphyromonas gingivalis and Filifactor alocis in Chronic Periodontitis Patients With Type 2 Diabetes Mellitus: A Clinico-Microbiological Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
backgroundPeriodontitis is a multifactorial and polymicrobial disease associated with microbial dysbiosis. Diabetes mellitus can modify the onset and course of periodontitis and has a bidirectional relationship with chronic periodontitis.
objectiveTo evaluate the effect of NSPT on subgingival detection of
methodsA total of 30 T2DM patients aged between 30 and 70 years with chronic periodontitis (PPD ≥5 mm, CAL ≥3 mm) voluntarily participated in this study. Clinical parameters like PPD and CAL were recorded at baseline, three months, and six months post-NSPT. Plaque samples from subgingival sites were collected from the deepest pockets and analysed for
resultsNSPT resulted in improvements that are statistically significant in PPD and CAL measurements (p < 0.05) over the six months. PCR analysis revealed a statistically significant percentage reduction of
conclusionNSPT was associated with improved clinical periodontal status and reduced microbial presence of key periodontal pathogens in T2DM patients. The findings of the present study suggest that NSPT contributes significantly to the improvement of periodontal health in diabetic patients.
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