Evidence map›Paper›PMID 41393529›Full record

ArticleActa ortopedica brasileira2025

RETROSPECTIVE ANALYSIS OF THE IMPACT OF NEGATIVE PRESSURE WOUND THERAPY ON COMPLICATIONS OF DELAYED COVERAGE OF IIIB EXPOSED TIBIAL FRACTURES.

Theodoro da Cunha Gonzalez, Ivan Ribaric, Yuri Macari Gomes, Mbilu Miguel André, Fernando Quissolo Dalaia Zua, Maria Adelaide de Miranda Gonçalves, Mauricio Ivo, Marcos de Camargo Leonhardt, Jorge Dos Santos Silva, Kodi Edson Kojima

Abstract read
In one paragraph

Article in Acta ortopedica brasileira, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Theodoro da Cunha GonzalezUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas (HCFMUSP), Grupo de Trauma, Instituto de Ortopedia e Traumatologia, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0009-0007-2549-3955
Ivan RibaricUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas (HCFMUSP), Grupo de Trauma, Instituto de Ortopedia e Traumatologia, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0009-0005-2487-8437
Yuri Macari GomesUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas (HCFMUSP), Grupo de Trauma, Instituto de Ortopedia e Traumatologia, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0009-0002-1184-7867
Mbilu Miguel AndréUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas (HCFMUSP), Grupo de Trauma, Instituto de Ortopedia e Traumatologia, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0009-0009-1260-0672
Fernando Quissolo Dalaia ZuaUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas (HCFMUSP), Grupo de Trauma, Instituto de Ortopedia e Traumatologia, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0009-0002-4259-3660
Maria Adelaide de Miranda GonçalvesUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas (HCFMUSP), Grupo de Trauma, Instituto de Ortopedia e Traumatologia, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0003-3957-6288
Mauricio IvoUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas (HCFMUSP), Grupo de Trauma, Instituto de Ortopedia e Traumatologia, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0001-6807-7555
Marcos de Camargo LeonhardtUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas (HCFMUSP), Grupo de Trauma, Instituto de Ortopedia e Traumatologia, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-0359-9704
Jorge Dos Santos SilvaUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas (HCFMUSP), Grupo de Trauma, Instituto de Ortopedia e Traumatologia, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0001-8901-3120
Kodi Edson KojimaUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas (HCFMUSP), Grupo de Trauma, Instituto de Ortopedia e Traumatologia, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0001-9543-081X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate whether NPWT in delayed coverage of Gustilo-Anderson Type IIIB open tibial fractures reduces the complication rate, including deep infection, nonunion, and amputation. Methods: Retrospective case series including patients with Gustilo-Anderson Type IIIB open tibial shaft fractures treated between January 2014 and December 2017 with NPWT. The outcome measures were incidence of deep infection, nonunion, and amputation. Analysis of time to coverage (within 7 days vs. after 7 days) and type of soft tissue coverage. Results: 26 patients with open tibial shaft fractures, predominantly male (96.2%), mean age 33.4 ± 13.9 years. Seven patients (26.9%) received coverage within 7 days; 19 patients (73.1%) received delayed coverage. The flap types were Myocutaneous (42.3%), microsurgical (34.6%), fasciocutaneous (23.1%). The overall infection rate was 50%, no significant difference between early (57.1%) and delayed (47.4%) coverage groups (p > 0.999). No amputations in the early coverage group; 2 (10.5%) in the delayed coverage group. Nonunion rates were 42.9% (early) and 36.8% (delayed). Overall complication rate: 85.7% (early) vs. 57.9% (delayed) (p = 0.357). Conclusion: NPWT may exert a protective effect in cases of delayed coverage by isolating the wound and promoting healing.

Indexed as

AmputationFracturesNegative-Pressure Wound TherapyUnunited

Identifiers

PMID41393529
PMCPMC12696736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.