Analytical cohort study on lymph node dissection extent and survival outcomes among esophageal cancer patients.

Yeruva Bheemeswara Reddy, Brinda Ganesh Kolar, Vishal Mruthyunjaya Kalmani, Dhyaneshwar Ra, Poornima Venkatraman

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Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 authors.

Yeruva Bheemeswara ReddyDepartment of Surgery, Santhiram Medical College, Andhra Pradesh, India.

Brinda Ganesh KolarDepartment of Cardiology, University Hospitals Bristol and Weston, South West England, United Kingdom.

Vishal Mruthyunjaya KalmaniDepartment of Surgery, Barking Havering and Redbridge University Hospitals NHS Trust, Essex, United Kingdom.

Dhyaneshwar RaDepartment of General Surgery, Government Stanley Medical College Chennai, Tamil Nadu, India.

Poornima VenkatramanDepartment of Surgery, Davao Medical School Foundation, Philippines, Asia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relationship between lymphadenectomy extent and survival among 138 esophageal cancer patients undergoing curative esophagectomy is of interest. Patients were grouped based on lymph node dissection: limited (<15 nodes), standard (15-29), and extended (≥30). Five-year survival improved with increasing nodal yield, especially in node-negative and early-stage patients. Multivariate analysis confirmed extended dissection as an independent predictor of better survival. These findings support a more extensive lymphadenectomy approach to optimize long-term oncologic outcomes.

Indexed as

cohort studyEsophageal canceresophagectomylymphadenectomynodal yieldsurgical oncologysurvival outcomes

Identifiers

PMID41393493

DOI10.6026/973206300212914

PMCPMC12697419

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