Alveolar-derived autologous blood clot as a scaffold for regenerative endodontic treatment: An observational study.

Gopikrishnan P B, Rajeswari Putchala, Vankala Gautam, Aparna Srivastava, Rahul Tiwari, Heena Dixit, Deepak Sharma

Abstract read

In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Gopikrishnan P BDepartment of Conservative and Endodontics, AL -AZHAR DENTAL COLLEGE, Thodupuzha, Kerala, India.

Rajeswari PutchalaDepartment of Conservative & Endodontics, ST. Joseph's Dental College, Duggirala, NTR University of health sciences, Andhra Pradesh, India.

Vankala GautamDepartment of Conservative & Endodontics, ST. Joseph's Dental College, Duggirala, NTR University of health sciences, Andhra Pradesh, India.

Aparna SrivastavaDepartment of Conservative Dentistry and Endodontics, Buddha Institute of Dental Sciences and Hospital, Patna, Bihar, India.

Rahul TiwariDepartment of Oral and Maxillofacial Surgery, RKDF Dental College and Research Centre, Sarvepalli Radhakrishnan University, Bhopal, Madhya Pradesh, India, India.

Heena DixitDepartment of Hospital Administration, Index Institute of Management, Arts and Science, Malwanchal University, Index City, Nemawar Road, Indore, Madhya Pradesh, India.

Deepak SharmaDepartment of Hospital Administration, Index Institute of Management, Arts and Science, Malwanchal University, Index City, Nemawar Road, Indore, Madhya Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regenerative endodontic treatment (RET) has transformed the management of immature necrotic permanent teeth by promoting biological healing and root development. Hence, a total of 20 patients aged 8-16 years with necrotic immature anterior teeth were enrolled. Blood was collected from a fresh alveolar socket and introduced into the canal space following canal disinfection with triple antibiotic paste. 83.3% showed complete periapical healing, while 72.2% exhibited apical closure and root lengthening by 12 months. We further found that clinical signs such as pain, swelling and sinus tract were resolved in all cases.

Indexed as

apical closureblood clot scaffoldimmature teethRegenerative endodonticsroot development

Identifiers

PMID41393466

DOI10.6026/973206300212486

PMCPMC12697436

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