ArticleBioinformation2025
Growth factors and osseointegration in dental implants - A review.
Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Article
- The Association Between Dental Implant and Bone Graft Failure and the Levels of Vitamin D and LDL Cholesterol: Retrospective Clinical Study.Dentistry journal · 2026Article
- Fueling failure or fostering fusion? A critical review of the potential effect of ketogenic, intermittent fasting, and low-carbohydrate diets on dental implant osseointegration.The Saudi dental journal · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osseointegration is essential for the long-term success of dental implants. However, achieving consistent and rapid integration remains challenging. Growth factors like PDGF, BMPs, TGF-β, IGF, VEGF, PRP and PRF have shown potential to enhance bone healing and implant stability. These agents promote osteoblast activity, angiogenesis and matrix formation, accelerating peri-implant bone regeneration. Delivery methods such as platelet concentrates, surface coatings and biomaterial integration have demonstrated promising outcomes. Therefore, it is of interest to review summarizing the biological rationale, clinical evidence, application techniques and future prospects of growth factor use in implant dentistry.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.