Evidence map›Paper›PMID 41393433›Full record

ArticleBioinformation2025

Thyroid dysfunction in non-alcoholic fatty liver disease: A case-control study.

Harshit Malkan, Bhavita Patel, Mahesh G Solu, Tejas D Patel, Mahammed Kaif Mubrakhusen Bhaniya

Abstract read
In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Harshit MalkanDepartment of General Medicine, Dr. Kiran C Patel Medical College and Research Institute, Bharuch, Gujarat, India.
Bhavita PatelDepartment of Biochemistry, Dr. Kiran C Patel Medical College and Research institute, Bharuch, Gujarat, India.
Mahesh G SoluDepartment of General Medicine, Dr. Kiran C Patel Medical College and Research Institute, Bharuch, Gujarat, India.
Tejas D PatelDepartment of Orthopaedic Surgery, Dr. Kiran C Patel Medical College & Research Institute, Bharuch, Gujarat, India.
Mahammed Kaif Mubrakhusen BhaniyaTrauma Centre, Dr Kiran C Patel Medical College and Research institute, Bharuch, Gujarat, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-alcoholic fatty liver disease (NAFLD) is increasingly recognized as a hepatic manifestation of metabolic dysfunction, with emerging evidence linking it to thyroid abnormalities. In this case-control study of 120 adults, thyroid dysfunction was more prevalent in NAFLD cases, with 20% having overt hypothyroidism and 5% subclinical hypothyroidism. Thyroid dysfunction increased with NAFLD severity, with overt hypothyroidism observed in 66.7% of Grade 3 cases. These findings highlight a strong association between worsening thyroid function and NAFLD severity, suggesting the need for routine thyroid screening in NAFLD management.

Indexed as

Metabolic dysfunctionnon-alcoholic fatty liver disease (NAFLD)thyroid dysfunction

Identifiers

PMID41393433
PMCPMC12697489

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.