ArticleBioinformation2025
Effect of leukoreduction in preventing febrile transfusion reactions.
Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Febrile non-hemolytic transfusion reactions (FNHTRs) remain one of the most common adverse events associated with packed red blood cell (PRBC) transfusions. Therefore, it is of interest to compare the efficacy of leukoreduction in the prevention of febrile transfusion reactions in PRBC-transfused patients using the TACE 2 automatic component extractor and Terumo Penpol blood bags. 600 PRBC transfusions were included in the analysis, of which 300 were leukoreduced and 300 were not leukoreduced. The standard operating procedures for leukoreduction were adopted with the help of the TACE 2 device and the rate of FNHTRs was noted and compared between the two groups. Leukoreduction greatly minimized the occurrence of febrile non-hemolytic transfusion reactions. Its application with automated extraction systems such as TACE 2 and quality blood bags like those of Terumo Penpol provided safe, effective and repeatable results.
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