Evidence map›Paper›PMID 41393393›Full record

ArticleBioinformation2025

Clinical evaluation of 3D printing and tissue engineering in craniofacial reconstruction: A prospective observational study.

Subramanian P, Timbadiya Vijaykumar Mansukhbhai, Parth Shailesh Bhatt, Shivalika Bhatnagar, Rashmi Laddha, Rishi Desai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Subramanian PDepartment of Oral and Maxillofacial Surgery, Dhanalakshmi Srinivasan Dental College, Perambalur, Tamil Nadu, India.
Timbadiya Vijaykumar MansukhbhaiDepartment of Oral Pathology and Microbiology, Rishiraj College of Dental Science and Research Centre Bhopal, Madhya Pradesh, India.
Parth Shailesh BhattDepartment of Pathology, Dr. N.D. Desai Faculty of Medical Science & Research, Dharmsinh Desai University, Nadiad, Gujarat, India.
Shivalika BhatnagarDepartment of Dentistry, DY Patil University School of Dentistry, Nerul, Navi Mumbai, Maharashtra, India.
Rashmi LaddhaDepartment of periodontology Dr RR Kambe Dental college and hospital Kanheri, Akola, Maharashtra, India.
Rishi DesaiDepartment of Dentistry, DY Patil University School of Dentistry, Nerul, Navi Mumbai, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The clinical results of tissue engineering and 3D printing in craniofacial reconstruction in 60 patients followed up over 3 years. Patient-specific implants and tissue-engineered scaffolds were created with state-of-the-art 3D printing techniques together with autologous stem cells and growth factors. Excellent success rates were attained with 92% implant integration, 88% satisfaction with aesthetics, and 85% return to function, with complications being restricted to 10% and treated conservatively. The technique decreased operative time, hospital stay and total cost of treatment substantially when compared with traditional techniques. Thus, we show the clinical application of 3D printing and tissue engineering as an effective, safe, and economically viable method in craniofacial reconstructive surgery.

Indexed as

3D printingbiocompatibilityCraniofacial reconstructionpatient-specific implantsprostheticsregenerative medicinetissue engineering

Identifiers

PMID41393393
PMCPMC12697462

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.