ArticleFrontiers in cardiovascular medicine2025
Fractal analysis of left ventricular trabeculae in hypertensive patients with heart failure: a 3.0 T cardiac magnetic resonance study.
Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Endocardial trabecular hyperplasia due to hemodynamic stress reflects phenotypic variability in disease progression. Employing fractal analysis, this study quantified left ventricular (LV) myocardial trabecular complexity in hypertensive patients with and without heart failure (HF) to evaluate its diagnostic utility for HF. Methods: This study retrospectively enrolled 146 hypertensive patients (77 with HF, 69 without), grouped into HTN-HF ( Results: Five fractal dimensions were derived: global FD, along with mean/maximal apical FD and mean/maximal basal FD. Compared with healthy controls, HF patients showed significantly elevated left ventricular fractal dimensions (all Conclusions: CMR fractal analysis provides a feasible technique for quantifying LV myocardial trabecular complexity in hypertensive heart failure patients. In conclusion, our study demonstrates the potential of fractal analysis to provide incremental diagnostic value for heart failure within the hypertensive population. Integration of FD into clinical diagnostic models may enhance diagnostic performance.
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