ArticleFrontiers in medicine2025
Dynamic hyperinflation occurs in healthy subjects during maximal voluntary ventilation.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Background: Dynamic hyperinflation (DH) commonly occurs during maximum voluntary ventilation (MVV) in obstructive lung diseases and is usually attributed to expiratory flow limitation. However, in healthy individuals, maximal effort typically remains insufficient to induce DH. This study aimed to determine whether DH can also develop during MVV in normal subjects without expiratory flow limitation, challenging the current concepts of its occurrence in physiological conditions. Methods: Forty-three healthy subjects (25 males/18 females; 40-68 yrs; FEV Results: DH occurred at or below 100 breaths.min Conclusion: DH can occur at low and variable breathing frequencies during MVV in healthy subjects. The onset of DH may be related to the mechanical thoracopulmonary state at rest, suggesting that the baseline lung mechanics may determine the susceptibility to DH during high-intensity ventilatory maneuvers.
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